| Assisted hatching is more effective when embryo quality was optimal in previous failed IVF/ICSI cycles. | |
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MedLine Citation:
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PMID: 17365461 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Assisted hatching (AH) was developed as a possible solution to repeated implantation failure. The aim of this analysis was to examine the relationship between the morphology of embryos in a previous cycle on outcome in a subsequent cycle with AH. A total of 175 AH cycles performed after previous failed ART without hatching were divided into group A with optimal and group B with suboptimal embryos transferred previously. The groups were similar in terms of demographic and cycle characteristics. In group A, there was a significant improvement (p<0.001) in implantation (28.8 vs 5.1%), clinical pregnancy (41.9 vs 12.1%) and live birth rate (38.5 vs 8.6%) compared with group B. The data suggest that the prognosis for treatment is better if AH is performed after failure despite optimal embryos compared with failure associated with suboptimal embryos and embryo quality is the most significant factor affecting outcome. |
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Authors:
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J Grace; V Bolton; P Braude; Y Khalaf |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Volume: 27 ISSN: 0144-3615 ISO Abbreviation: J Obstet Gynaecol Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-03-16 Completed Date: 2007-05-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309140 Medline TA: J Obstet Gynaecol Country: England |
Other Details:
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Languages: eng Pagination: 56-60 Citation Subset: IM |
Affiliation:
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Assisted Conception Unit, King's College London, School of Medicine, Guy's and St Thomas' Hospital, London, UK. jan.grace@gstt.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Embryo Disposition* Female Humans Middle Aged Pregnancy Pregnancy Outcome* Reproductive Techniques, Assisted* Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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