| Assessment of wall shear stress changes in arteries and veins of arteriovenous polytetrafluoroethylene grafts using magnetic resonance imaging. | |
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MedLine Citation:
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PMID: 16729233 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of the study was to determine simultaneously the temporal changes in luminal vessel area, blood flow, and wall shear stress (WSS) in both the anastomosed artery (AA) and vein (AV) of arteriovenous polytetrafluoroethylene (PTFE) grafts. PTFE grafts were placed from the iliac artery to the ipsilateral iliac vein in 12 castrated juvenile male pigs. Contrast-enhanced magnetic resonance angiography with cine phase-contrast magnetic resonance imaging was performed. Luminal vessel area, blood flow, and WSS in the aorta, AA, AV, and inferior vena cava were determined at 3 days (D3), 7 days (D7), and 14 days (D14) after graft placement. Elastin von Gieson staining of the AV was performed. The average WSS of the AA was highest at D3 and then decreased by D7 and D14. In contrast, the average WSS and intima-to-media ratio of the AV increased from D3 to D7 and peaked by D14. Similarly, the average area of the AA was highest by D7 and began to approximate the control artery by D14. The average area of the AV had decreased to its lowest by D7. High blood flows through the AA causes a decrease in average WSS and increase in the average luminal vessel area, whereas at the AV, the average WSS and intima-to-media ratio both increase while the average luminal vessel area decreases. |
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Authors:
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Sanjay Misra; David A Woodrum; Jay Homburger; Stephane Elkouri; Jayawant N Mandrekar; Victor Barocas; James F Glockner; Dheeraj K Rajan; Debabrata Mukhopadhyay |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cardiovascular and interventional radiology Volume: 29 ISSN: 0174-1551 ISO Abbreviation: Cardiovasc Intervent Radiol Publication Date: 2006 Jul-Aug |
Date Detail:
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Created Date: 2006-05-26 Completed Date: 2006-11-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8003538 Medline TA: Cardiovasc Intervent Radiol Country: United States |
Other Details:
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Languages: eng Pagination: 624-9 Citation Subset: IM |
Affiliation:
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Department of Radiology, Mayo Clinic, Rochester, MN, USA. Misra.Sanjay@mayo.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Arteriovenous Fistula / diagnosis, pathology, surgery* Blood Flow Velocity Contrast Media Disease Models, Animal Humans Magnetic Resonance Angiography Magnetic Resonance Imaging / methods* Phantoms, Imaging Polytetrafluoroethylene Renal Dialysis Stress, Mechanical |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 9002-84-0/Polytetrafluoroethylene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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