Document Detail

Assessment of the viscosity of the pulmonary artery wall.
MedLine Citation:
PMID:  11292119     Owner:  NLM     Status:  MEDLINE    
Large artery wall viscosity reduces the efficiency of heart/vessel coupling. The aim of the present study was to assess pulmonary artery wall viscosity through comparison of the static (Dst) and dynamic distensibility (Ddyn) of the vessel wall. Right pulmonary artery pressure and diameter was measured in 13 patients and eight healthy volunteers. Ddyn was calculated as the relative change in end-diastolic diameter induced by the pressure pulse, and Dst as the relative change in mean diameter induced by the change in mean pressure during steady-state exercise. Dst did not differ significantly from Ddyn (mean+/-SD 22.8+/-19.2 versus 21.0+/-18.3 10(-3) mmHg(-1)), as tested by paired t-test and analysis of covariance, with age as covariant. End-diastolic diameter increased, whereas Dst and Ddyn decreased as a function of age (r=-0.69 and -0.67, respectively; p<0.01 for both). Ddyn did not change from rest to exercise in spite of a 23+/-16-beats-min(-1) increase in cardiac frequency. Pulmonary artery wall viscosity was negligible and no increase in wall viscosity occurred during cardioacceleration.
Z Visontai; Z Lénárd; K Karlocai; M Kollai
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The European respiratory journal     Volume:  16     ISSN:  0903-1936     ISO Abbreviation:  Eur. Respir. J.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-04-06     Completed Date:  2001-07-05     Revised Date:  2013-05-23    
Medline Journal Info:
Nlm Unique ID:  8803460     Medline TA:  Eur Respir J     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  1134-41     Citation Subset:  IM    
Clinical Research Dept and Second Institute of Physiology, Semmelweis University, Budapest, Hungary.
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MeSH Terms
Age Factors
Aged, 80 and over
Exercise Test
Heart Rate / physiology
Hypertension, Pulmonary / physiopathology
Middle Aged
Pulmonary Artery / physiology*
Pulmonary Wedge Pressure / physiology
Reference Values
Vasodilation / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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