| Assessment of viable myocardium and prediction of postoperative improvement in left ventricular function in patients with severe left ventricular dysfunction by quantitative planar stress-redistribution-reinjection 201-T1 imaging. | |
| | |
MedLine Citation:
|
PMID: 9049684 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A noninvasive approach to determine viable but asynergic myocardium will be clinically significant in identifying patients with coronary artery disease and severe left ventricular dysfunction who will benefit most from coronary bypass surgery. Accordingly, 12 patients (mean ejection fraction 0.32 +/- 0.03) underwent quantitative planar stress-redistribution-reinjection thallium scintigraphy and radionuclide ventriculography before and 8 weeks after revascularization for viability and segmental and global left ventricular function assessment, respectively. Reinjection scan showed new fill-in in 63% of segments without redistribution. Postoperative improvement in perfusion and function of asynergic segments were significantly better in viable compared to nonviable segments (P < 0.001, P < 0.01, respectively) with a strong correlation between improvement in 201-T1 uptake and function (P < 0.001). When adequacy of revascularization was considered, the predictive value of a positive preoperative viability test for functional improvement was 83%. Finally, mean ejection fraction and global wall motion score increased significantly after revascularization for the group as a whole (0.32 +/- 0.03 to 0.44 +/- 0.04, P < 0.001 and 24.08 +/- 2.90 to 33.16 +/- 3.32, P < 0.001, respectively). Thus, preoperative quantitative planar stress-redistribution-reinjection thallium imaging detects viable but asynergic segments which improve function postoperatively and may be valuable in selection of patients with severe left ventricular dysfunction for revascularization. |
| | |
Authors:
|
M Gürsürer; A E Pinarli; M Aksoy; R Tosun; K Yeşilçimen; B Ersek |
Related Documents
:
|
2295724 - Quantitation of acute myocardial infarct size by nuclear magnetic resonance imaging. 11702104 - Myocardial metabolism of 123i-bmipp during low-flow ischaemia in an experimental model:... 20808984 - Resting electrocardiogram and stress myocardial perfusion imaging in the determination ... 10853814 - Alteration of myocardial metaiodobenzylguanidine uptake after treatment of phaeochromoc... 15965564 - Elevated troponins and the churg-strauss syndrome: a case report. 9201474 - Nitinol self-expanding stents: when severe twisting occurs, self-expansion may ensue af... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: International journal of cardiology Volume: 58 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 1997 Jan |
Date Detail:
|
Created Date: 1997-05-27 Completed Date: 1997-05-27 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: IRELAND |
Other Details:
|
Languages: eng Pagination: 179-84 Citation Subset: IM |
Affiliation:
|
Prof. Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center, Istanbul, Turkey. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Chi-Square Distribution Coronary Artery Bypass / methods* Evaluation Studies as Topic Female Humans Male Middle Aged Predictive Value of Tests Prognosis Prospective Studies Radionuclide Ventriculography / methods, standards* Thallium Radioisotopes / diagnostic use Treatment Outcome Ventricular Dysfunction, Left / radionuclide imaging*, surgery* |
| Chemical | |
Reg. No./Substance:
|
0/Thallium Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Inflammatory valvular prolapse produced by acute rheumatic carditis: echocardiographic analysis of 6...
Next Document: Primary amyloidosis and syncope.