Document Detail

Assessment of various factors influencing esophageal pressure measurement. II. Significance of physiological factors in intraluminal manometry.
MedLine Citation:
PMID:  7374097     Owner:  NLM     Status:  MEDLINE    
In the second part of this study the effect of age, sex, body size, body weight and timing of the manometric examination (morning vs. noon) on esophageal pressure measurement was investigated in a total of 119 healthy subjects, using an electromagnetic microtransducer. Additionally intraindividual variation of pressures was studied over a period of 6 months. Of these parameters only age influenced upper esophageal sphincter (UES) pressure significantly: The mean UES pressure of younger subjects (20-49 years) was significantly higher (144.4 +/- 8.6 mmHg) compared to that of older subjects (50-80 years) where a mean pressure of 103.4 +/- 7.2 mmHg was recorded (p less than 0.0005). Intraindividual variation of pressures in the lower esophageal sphincter (LES) was considerable but exceeded only in a few cases the normal pressure range which was defined as M +/- 2 S. The results indicate that age, sex, different body weight and body size do not influence significantly the normal values obtained by a quantitative manometric method. In UES manometry however, the diminished resting pressure in the older patient must be taken into account.
T R Weihrauch; P Vallerius; H Alpers; K Ewe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Klinische Wochenschrift     Volume:  58     ISSN:  0023-2173     ISO Abbreviation:  Klin. Wochenschr.     Publication Date:  1980 Mar 
Date Detail:
Created Date:  1980-07-26     Completed Date:  1980-07-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985205R     Medline TA:  Klin Wochenschr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  287-92     Citation Subset:  IM    
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MeSH Terms
Age Factors
Body Weight
Circadian Rhythm
Esophagus / physiology*
Middle Aged
Reference Values
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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