| Assessment of three AC electroosmotic flow protocols for mixing in microfluidic channel. | |
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MedLine Citation:
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PMID: 19370247 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study performs an experimental investigation into the micromixer capabilities of three different protocols of AC electroosmotic flow (AC EOF), namely capacitive charging (CC), Faradaic charging (FC) and asymmetric polarization (AP). The results reveal that the vortices generated by the FC protocol (the frequency is around 50-350 Hz) are stronger than those induced by the CC protocol (the frequency is higher than 350 Hz), and therefore provide an improved mixing effect. However, in the FC protocol, the frequency of the external AC voltage must be carefully controlled to avoid damaging electrodes as a result of Faradaic reactions. The experimental results indicate that the AP polarization effect (the applied voltage and frequency are V(1) = 1 V(pp) and V(2) = 20 V(pp)/5 kHz) induces more powerful vortices than either the CC protocol or the FC protocol, and therefore yields a better mixing performance. Two AP-based micromixers are fabricated with symmetric and asymmetric electrode configurations, respectively. The mixing indices achieved by the two devices after an elapsed time of 60 seconds are found to be 56.49 % and 71.77 %, respectively. This result shows that of the two devices, an asymmetric electrode configuration represents a more suitable choice for micromixer in microfluidic devices. |
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Authors:
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Jia-Kun Chen; Chi-Neng Weng; Ruey-Jen Yang |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-02-03 |
Journal Detail:
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Title: Lab on a chip Volume: 9 ISSN: 1473-0197 ISO Abbreviation: Lab Chip Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-16 Completed Date: 2009-06-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101128948 Medline TA: Lab Chip Country: England |
Other Details:
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Languages: eng Pagination: 1267-73 Citation Subset: IM |
Affiliation:
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Department of Engineering Science, National Cheng Kung University, Tainan, Taiwan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Complex Mixtures
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chemistry*,
isolation & purification*,
radiation effects Computer Simulation Computer-Aided Design Electromagnetic Fields Electrophoresis / instrumentation*, methods Equipment Design Equipment Failure Analysis Microfluidic Analytical Techniques / instrumentation* Models, Chemical* Osmotic Pressure Reproducibility of Results Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Complex Mixtures |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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