| Assessment of synovitis in the osteoarthritic knee: Comparison between manual segmentation, semiautomated segmentation, and semiquantitative assessment using contrast-enhanced fat-suppressed T1-weighted MRI. | |
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MedLine Citation:
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PMID: 20665803 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Osteoarthritic joints regularly exhibit synovitis, which is ideally assessed on contrast-enhanced MRI. Manual segmentation is the reference standard for volumetric analysis but is labor intensive. The aim was to evaluate alternative semiautomated approaches of targeted thresholding and gaussian deconvolution. Volumetric and semiquantitative synovitis assessment was compared in addition. Thirty-two knees with osteoarthritis were scanned on a 1.5-T system. Synovitis volumes were plotted against each other and distributions fit with linear functions. The relationship between semiquantitative scores and synovitis volumes was assessed using Spearman's correlation coefficient. Semiautomated volume measurement was more time efficient than manual segmentation and showed a high correlation with manual analysis (R(2) = 0.88 and 0.82). Manual segmentation was correlated with summed and with maximum semiquantitative synovitis scores (rho = 0.71 and 0.47). In conclusion, semiautomated analysis provides comparable quantitative results when compared to manual segmentation but is approximately five times more time efficient. Semiquantitative assessment adds anatomic information on synovitis distribution. |
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Authors:
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Amber Kassel Fotinos-Hoyer; Ali Guermazi; Hernán Jara; Felix Eckstein; Al Ozonoff; Hussain Khard; Alexander Norbash; Klaus Bohndorf; Frank W Roemer |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 64 ISSN: 1522-2594 ISO Abbreviation: Magn Reson Med Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-28 Completed Date: 2011-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
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Languages: eng Pagination: 604-9 Citation Subset: IM |
Affiliation:
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Department of Radiology, Boston University Medical Center, Boston, Massachusetts, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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pathology* Aged Algorithms* Contrast Media Female Gadolinium DTPA / diagnostic use* Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods* Magnetic Resonance Imaging Male Middle Aged Osteoarthritis, Knee / complications, pathology* Pattern Recognition, Automated / methods* Reproducibility of Results Sensitivity and Specificity Subtraction Technique Synovitis / etiology, pathology* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 122795-43-1/gadodiamide; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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