| Assessment of stenosis in vascular access grafts. | |
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MedLine Citation:
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PMID: 15209853 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The major complication that occurs with grafts used as vascular access for hemodialysis, is stenosis at the venous anastomosis or in the draining vein. 75% area stenosis is considered significant as thrombotic occlusion may occur. The aim of this experimental study was to evaluate invasive and noninvasive indices to detect significant stenoses in a vascular access graft. A compliant underarm loop graft in vitro model was built and studied with 50, 65, 80, and 90% stenosis at flow rates of 500, 1000, and 1500 mL/min. Flow in the system was pulsatile. Velocity was measured with ultrasound Doppler and the pressure was measured invasively. The resistance index (RI), p(venous line)/MAP, and the newly introduced pressure ratio (PR) were calculated and compared. A stenosis can be suspected when a high frequency ultrasound velocity signal develops at the venous anastomosis. RI > 1 confirms a very severe stenosis (90%). The parameter PR < 8% confirms significant stenoses showing its clinical relevancy. |
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Authors:
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Ilse Van Tricht; Dirk De Wachter; Daniel Vanhercke; Jan Tordoir; Pascal Verdonck |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Artificial organs Volume: 28 ISSN: 0160-564X ISO Abbreviation: Artif Organs Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-06-22 Completed Date: 2004-09-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802778 Medline TA: Artif Organs Country: United States |
Other Details:
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Languages: eng Pagination: 617-22 Citation Subset: IM |
Affiliation:
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Hydraulics Laboratory, Institute Biomedical Technology, Ghent University, Ghent, Belgium. Vantricht@ugent.be |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anastomosis, Surgical Arteriovenous Shunt, Surgical* Blood Pressure Blood Vessel Prosthesis* Constriction, Pathologic Hemodynamics Humans Models, Cardiovascular Polytetrafluoroethylene Ultrasonography, Doppler Vascular Resistance |
| Chemical | |
Reg. No./Substance:
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9002-84-0/Polytetrafluoroethylene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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