| Assessment of skeletal maturation in infants: comparison between two methods in hypothyroid patients. | |
| | |
MedLine Citation:
|
PMID: 9716638 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Conventional skeletal radiography is the standard technique for assessing skeletal age. However, radiography cannot demonstrate cartilage and is therefore of lesser value in infancy when the ossification centres are composed mainly of cartilage. By comparison, US clearly demonstrates cartilage and bone. OBJECTIVE: In the present study, we compared radiography and sonography for the assessment of skeletal age in neonates and infants. MATERIALS AND METHODS: Because delayed skeletal maturation is a feature of congenital hypothyroidism and assessment of skeletal age is routinely performed in our centre, we studied 55 hypothyroid infants (aged 7-66 days). AP radiographs and sonograms, acquired using high-frequency scanners, were obtained and dimensions of the distal femoral epiphyseal ossification centre (DFE) were compared. RESULTS: Measurements of DFE by the two methods showed excellent correlation (R = 0.94, P = 0.0001). Radiographs did not demonstrate a DFE in 11 infants, and US did not show it in 6. In no infant did radiography demonstrate DFE not seen by US. Moreover, DFE dimensions on US were larger than those measured on radiographs. Infants with absent thyroid gland had a DFE significantly smaller than those infants with ectopic or normally placed glands (P < 0.001), on both radiographs and sonograms. CONCLUSION: Our data suggest that sonography is a valid alternative to standard radiography for the assessment of skeletal age in infants. |
| | |
Authors:
|
P L Paesano; M C Vigone; V Siragusa; G Chiumello; A Del Maschio; S Mora |
Related Documents
:
|
16183538 - Hormonal contraception: noncontraceptive benefits and medical contraindications. 2753978 - Thyroid function in neonates from goitrous and nongoitrous iodine-sufficient areas. 6744638 - Antithyroid treatment of maternal hyperthyroidism during lactation. 19007678 - Iodine balance, iatrogenic excess, and thyroid dysfunction in premature newborns. 3393328 - A national study of sudden infant death syndrome in new zealand. 7674058 - Station in early labor in nulliparous women at term. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Pediatric radiology Volume: 28 ISSN: 0301-0449 ISO Abbreviation: Pediatr Radiol Publication Date: 1998 Aug |
Date Detail:
|
Created Date: 1998-11-30 Completed Date: 1998-11-30 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0365332 Medline TA: Pediatr Radiol Country: GERMANY |
Other Details:
|
Languages: eng Pagination: 622-6 Citation Subset: IM |
Affiliation:
|
Department of Paediatrics, Scientific Institute H San Raffaele, University of Milan, Milan, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age Determination by Skeleton
/
methods* Analysis of Variance Congenital Hypothyroidism* Enzyme-Linked Immunosorbent Assay Female Humans Infant Infant, Newborn Knee / radiography*, ultrasonography* Male Sensitivity and Specificity Thyrotropin / blood |
| Chemical | |
Reg. No./Substance:
|
9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Spondyloenchondrodysplasia: several phenotypes--the same syndrome.
Next Document: Uroradiology in the fetus and newborn: diagnosis and follow-up of congenital obstruction of the urin...