Document Detail


Assessment of seasonal variability of cytochemical responses to contaminant exposure in the blue mussel Mytilus edulis (complex).
MedLine Citation:
PMID:  12434218     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A selected suite of cytochemical parameters in Mytilus edulis are altered in response to field and laboratory exposure to chemical contaminants. These biomarkers include lysosomal stability, nicotinamide adenine dinucleotide phosphate (NADPH)-ferrihemoprotein reductase activity, liposfuscin deposition, and accumulation of lysosomal and cytoplasmic unsaturated neutral lipid. Normal variations in physiological processes (influenced by exogenous seasonal changes in temperature, salinity, food availability, etc.) may alter the sensitivity of these biomarkers to contaminant exposure. To address this issue, M. edulis (complex) were sampled monthly from a reference nonurban site (Coupeville, Penn Cove) and a polluted urban site (Seacrest, Elliott Bay) in Puget Sound, WA, for a period of 15 months. Physiological measurements including total length, total weight, somatic and mantle weights (an indication of gonadal development and reproductive status), condition index, and the presence or absence of hemic neoplasia (HN, or leukemia) were recorded. Significant differences in lysosomal stability, lysosomal and cytoplasmic unsaturated neutral lipids, lipofuscin deposition, and NADPH-ferrihemoprotein reductase activity in cells of the digestive gland or digestive tubules were generally found in mussels taken throughout the year from Seacrest compared to mussels sampled from Coupeville, consistent with exposure to chemical contaminants. No seasonally influenced suppression of the entire suite of parameters as measures of contaminant exposure was evident. Therefore these biomarkers can be used to evaluate contaminant exposure in mussels throughout the entire year.
Authors:
A N Kagley; R G Snider; P K Krishnakumar; E Casillas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of environmental contamination and toxicology     Volume:  44     ISSN:  0090-4341     ISO Abbreviation:  Arch. Environ. Contam. Toxicol.     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2002-11-15     Completed Date:  2003-05-13     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0357245     Medline TA:  Arch Environ Contam Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  43-52     Citation Subset:  IM    
Affiliation:
Environmental Conservation Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, Hatfield Marine Science Center, Newport, Oregon 97391, USA. anna.kagley@noaa.gov
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological*
Animals
Biological Markers / analysis*
Bivalvia / physiology*
Body Weight
Environmental Monitoring
Ferredoxin-NADP Reductase / analysis,  pharmacology
Lipid Metabolism
Lipofuscin / metabolism
Lysosomes / metabolism
Reproduction
Seasons
Water Pollutants / adverse effects*
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Lipofuscin; 0/Water Pollutants; EC 1.18.1.2/Ferredoxin-NADP Reductase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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