Document Detail

Assessment of renal function in workers previously exposed to cadmium.
MedLine Citation:
PMID:  3904816     Owner:  NLM     Status:  MEDLINE    
Cadmium induced renal effects were examined in 60 workers (58 men, 2 women) previously exposed to cadmium. Tubular damage in the form of beta 2-microglobulinuria was found in 40%, and urinary albumin and orosomucoid increased significantly with increasing urinary cadmium and increasing relative clearance of beta 2-microglobulin. It is suggested that increased albumin excretion is secondary to the tubular damage. In no case was typical glomerular proteinuria found that could be related to cadmium. Histories of renal stones were more common among the workers with high urinary cadmium concentrations. The glomerular filtration rate was measured in 17 of the workers who had pronounced tubular dysfunction. The average glomerular filtration rate for these men was less than the age adjusted predicted value (mean = 84%). Furthermore, there was a significant (p less than 0.05) correlation (r = -0.47) between tubular reabsorption loss and a decreased glomerular filtration rate.
C G Elinder; C Edling; E Lindberg; B Kågedal; O Vesterberg
Related Documents :
21927666 - The effect of antiviral therapy on serum cholesterol levels in chronic hepatitis c.
11327466 - Use of plasma clearance of iohexol for estimating glomerular filtration rate in cats.
21781066 - Cd26/dipeptidyl-peptidase iv and adenosine deaminase serum levels in psoriatic patients...
8445236 - Oral misoprostol or intravenous prostaglandin e2 do not improve renal function in patie...
11981386 - Hyperfibrinogenemia as a risk factor for sudden hearing loss.
11483796 - Association between serum macrophage colony-stimulating factor levels and monocyte and ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of industrial medicine     Volume:  42     ISSN:  0007-1072     ISO Abbreviation:  Br J Ind Med     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-12-26     Completed Date:  1985-12-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370637     Medline TA:  Br J Ind Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  754-60     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cadmium / adverse effects*,  urine
Glomerular Filtration Rate / drug effects
Kidney Calculi / chemically induced
Kidney Diseases / chemically induced*,  physiopathology
Kidney Function Tests
Middle Aged
Occupational Diseases / chemically induced*,  physiopathology
Orosomucoid / urine
beta 2-Microglobulin / urine
Reg. No./Substance:
0/Orosomucoid; 0/beta 2-Microglobulin; 7440-43-9/Cadmium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A study of the effects of treating platelets with paraformaldehyde for use in the platelet suspensio...
Next Document:  A multicentre prospective randomized controlled trial of induction of labour with an automatic close...