| Assessment of questionnaire validity for measuring total fat intake using plasma lipid levels as criteria. | |
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MedLine Citation:
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PMID: 11744515 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The validation of dietary total fat measurements has been elusive because no specific biomarker exists. In metabolic studies with controlled diets, plasma fasting triglyceride levels are reduced with higher fat intake and can thus serve as an "alloyed gold" standard. Participants in this cross-sectional analysis were 269 men aged 47-83 years from the Health Professionals Follow-up Study who completed a semiquantitative food frequency questionnaire and provided fasting blood specimens in 1994. In a multiple regression analysis adjusted for age; smoking; alcohol consumption; physical activity; body mass index; and intakes of protein, dietary fiber, and total energy, total fat intake was inversely associated with fasting triglycerides (for a fat increase of 1% of energy, triglyceride levels were lower by 2.5% (95% confidence interval: -3.7 to -1.3%, p = 0.0002)). For reported fat intakes of 20% or less of energy, the geometric mean fasting triglyceride level was 179, and for more than 40% of energy, it was 102 mg/dl. In addition, as predicted by metabolic studies, the inverse association between dietary fat and fasting triglyceride level was much stronger among overweight men than among men with a BMI of less than 25. These data provide additional evidence that informative measurements of dietary fat can be obtained by carefully constructed food frequency questionnaires. |
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Authors:
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W Willett; M Stampfer; N F Chu; D Spiegelman; M Holmes; E Rimm |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Validation Studies |
Journal Detail:
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Title: American journal of epidemiology Volume: 154 ISSN: 0002-9262 ISO Abbreviation: Am. J. Epidemiol. Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2001-12-17 Completed Date: 2002-01-15 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7910653 Medline TA: Am J Epidemiol Country: United States |
Other Details:
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Languages: eng Pagination: 1107-12 Citation Subset: IM |
Affiliation:
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Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA. walter.willett@channing.harvard.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Biological Markers / blood Body Mass Index Body Weight / physiology* Cholesterol, HDL / blood* Cohort Studies Cross-Sectional Studies Diet Surveys Dietary Fats / administration & dosage* Dietary Fiber / administration & dosage Dietary Proteins / administration & dosage Energy Intake / physiology Exercise Fasting / blood Follow-Up Studies Humans Male Middle Aged Prospective Studies Questionnaires / standards* Regression Analysis Reproducibility of Results Smoking Triglycerides / blood* |
| Grant Support | |
ID/Acronym/Agency:
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AA11181/AA/NIAAA NIH HHS; CA55075/CA/NCI NIH HHS; HL35464/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Cholesterol, HDL; 0/Dietary Fats; 0/Dietary Proteins; 0/Triglycerides |
| Comments/Corrections | |
Comment In:
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Am J Epidemiol. 2001 Dec 15;154(12):1100-2; discussion 1105-6
[PMID:
11744512
]
Int J Epidemiol. 2002 Jun;31(3):694-5 [PMID: 12162249 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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