Document Detail


Assessment of presence and characteristics of multipotent stromal cells in human endometrium and decidua.
MedLine Citation:
PMID:  20117049     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This review discusses the presence and characteristics of multipotent stromal cells in human endometrium and decidua. A number of research groups have reported the isolation and characterization of multipotent stromal cells from the basal layer of the endometrium, and in a single case just from the menstrual blood, i.e. the superficial functional layer. Similarly, multipotent pre-decidual stromal cells are isolated from early decidua and characterized accordingly. Multipotent endometrial stromal cells and multipotent decidual stromal cells are shown to express the basic features of adult stem cells, which are clonogenicity, self-renewal, a potential to differentiate into adipogenic, osteogenic, chrondrogenic, endothelial-like cells and a specific set of surface molecules (CD73, CD90 and CD105). So far, it is not clear whether the same population of multipotent stromal cells is isolated from the basal endometrium or early decidua because it has been shown that in some cases the differentiation potential of endometrial stromal cells is more restricted in comparison to the decidual stromal cells. It is reasonable to assume that it is one cell population under different control by hormonal, paracrine and autocrine factors. Thus far, the functions of these cells have not been convincingly revealed.
Authors:
Stanimir Kyurkchiev; Atanas Shterev; Rumen Dimitrov
Related Documents :
10330449 - Immunocytochemical localization of type 5 17beta-hydroxysteroid dehydrogenase in human ...
14518549 - Life cycle of decidual cells.
15642789 - Stimulation of a rat uterine stromal cell line in culture reveals a molecular switch fo...
19853659 - Matriptase/epithin participates in mammary epithelial cell growth and morphogenesis thr...
10356709 - Effects of neonatal diethylstilbestrol (des) exposure on morphology and growth patterns...
20035059 - Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation ...
4935379 - C1 inhibitor: evidence for decreased hepatic synthesis in hereditary angioneurotic edema.
12203399 - Involvement of cell cycle control in bleomycin-induced mutagen sensitivity.
12118559 - A review of human cell radiosensitivity in vitro.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-12-16
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  20     ISSN:  1472-6491     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-26     Completed Date:  2010-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  305-13     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Institute of Biology and Immunology of Reproduction Acad K Bratanov, Bulgarian Academy of Sciences, 73 Tzarigradsko shosse, 1113 Sofia, Bulgaria. kyurkch@hotmail.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Cell Differentiation
Cell Separation
Decidua / cytology*
Endometrium / cytology*
Female
Humans
Mesenchymal Stem Cells / immunology,  physiology
Mice
Multipotent Stem Cells / immunology,  physiology
Stromal Cells / cytology*,  immunology,  physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Contribution of in-vitro maturation in ovarian stimulation cycles of poor-responder patients.
Next Document:  Progressive alcohol-induced sperm alterations leading to spermatogenic arrest, which was reversed af...