| Assessment of prenatal exposure to persistent organohalogen compounds from cord blood serum analysis in two Mediterranean populations (Valencia and Menorca). | |
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MedLine Citation:
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PMID: 21152602 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Prenatal levels of organohalogen compounds (OHCs), including polybromodiphenyl ethers (PBDEs), polychlorobiphenyls (PCBs), hexachlorobenzene (HCB), hexachlorocyclohexanes and DDTs, have been investigated in two different cohorts from the Spanish Mediterranean area, Valencia and Menorca, by analysis of cord blood serum. Comparison of the observed median concentrations to other cohorts shows low PBDE levels (2.8-6.5 ng g(-1) lipid) but high values of HCB (0.68 ng ml(-1), 260 ng g(-1) lipid) and PCBs (0.65 ng ml(-1), 240 ng g(-1) lipid) in the cohort of Menorca indicating that Mediterranean areas, and not only high latitude regions, may contain population groups highly exposed to some of these pollutants. Significant differences in the concentrations of these compounds have been found between the two cohorts. Differences in maternal population such as age or body mass index cannot explain this variation. One possible cause of variability is the seven year time period elapsed between the two cohort recruitments but the strong differences observed do not allow exclusion of local diet differences. Thus, the different average PCB congener distributions between the two cohorts suggest an influence from materials containing diverse PCB mixtures. The congener mixtures found in Menorca could reflect a diet contribution from some western Mediterranean fish species. These results provide baseline information on prenatal OHC background levels in the Mediterranean area. |
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Authors:
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Esther Vizcaino; Joan O Grimalt; Daniel Carrizo; Maria-José Lopez-Espinosa; Sabrina Llop; Marisa Rebagliato; Ferran Ballester; Maties Torrent; Jordi Sunyer |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-12-13 |
Journal Detail:
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Title: Journal of environmental monitoring : JEM Volume: - ISSN: 1464-0333 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100968688 Medline TA: J Environ Monit Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDÆA-CSIC), Jordi Girona, 18, 08034, Barcelona, Catalonia, Spain. joan.grimalt@idaea.csic.es. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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