Document Detail

Assessment of the predictive value of serum progesterone levels on early pregnancy prognosis in spontaneous twin gestations: a prospective study.
MedLine Citation:
PMID:  18096295     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The aim of this study was to assess the predictive value of serum progesterone levels in early pregnancy prognosis in spontaneous dichorionic-diamniotic twin gestations. STUDY DESIGN: This study was carried out among 38 spontaneous dichorionic-diamniotic twin gestations between January 2003 and June 2005 in the Department of Obstetrics and Gynaecology at the Gulhane Military Medical Academy. Serum progesterone levels were measured at 7 and 10 weeks' gestation and pregnancies were followed until 14 gestational weeks by ultrasound examination. RESULTS: We found that a progesterone level of 58 nmol/l in the 7th gestational week and of 51 ng/ml at 10 gestational weeks has a predictive value for viable intrauterine twin pregnancies with 83% sensitivity and 69% specificity and 83% sensitivity and 84% specificity, respectively. CONCLUSION: Progesterone levels in the early gestational weeks may be a biochemical marker for the prediction of a twin pregnancy outcome and may reduce the number of ultrasound examinations.
Umit Goktolga; Sadettin Gungor; Seyit Temel Ceyhan; Ugur Keskin; Ulas Fidan; Kazim Gezginc; Iskender Baser
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Publication Detail:
Type:  Journal Article; Twin Study     Date:  2007-12-21
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  137     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-31     Completed Date:  2008-07-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  185-8     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Gulhane Military Medical Academy and Medical School, Ankara, Turkey. <>
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MeSH Terms
Biological Markers / blood
Predictive Value of Tests
Pregnancy Outcome
Pregnancy Trimester, First / blood*
Pregnancy, Multiple / blood*
Progesterone / blood*
Prospective Studies
Sensitivity and Specificity
Twins, Dizygotic*
Ultrasonography, Prenatal
Reg. No./Substance:
0/Biological Markers; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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