Document Detail


Assessment of phosphate binding by sevelamer carbonate powder for oral suspension mixed in foods.
MedLine Citation:
PMID:  22866363     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
This study investigated mixing sevelamer carbonate powder with foods and beverages other than water. Food samples, including applesauce, oatmeal, chicken, protein powder, scrambled eggs, ginger ale, and diet ginger ale, were subjected to an in vitro assay, and the difference in the amount of phosphate bound between samples pre-exposed to foods and samples where the drug was exposed to foods concurrently was determined Under these assay conditions, pre-exposure to sevelamer carbonate powder had no effect on the ability to bind phosphate. Clinical testing is needed to further evaluate this finding.
Authors:
Martin Hanus; Eugene Zhorov; Deborah Brommage; Melissa Plone; Stephen Randall Holmes-Farley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nephrology nursing journal : journal of the American Nephrology Nurses' Association     Volume:  39     ISSN:  1526-744X     ISO Abbreviation:  Nephrol Nurs J     Publication Date:    2012 May-Jun
Date Detail:
Created Date:  2012-08-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100909377     Medline TA:  Nephrol Nurs J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  239-43, 255     Citation Subset:  N    
Affiliation:
Analytical Research and Development, Genzyme Corporation, Waltham, MA, USA. martin.hanus@genzyme.com
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