Document Detail


Assessment of papillary muscle function in patients with inferior wall myocardial infarction using Doppler tissue imaging.
MedLine Citation:
PMID:  16084333     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: We sought to assess the relationship between infarct status and systolic contractile function of papillary muscle (PM) for patients with inferior wall myocardial infarction (MI). METHODS: Peak systolic velocity (V) of posteromedial PM, systolic strain (epsilon) of posteromedial PM (epsilonPM), V of adjacent inferior wall, and of adjacent inferior wall (epsilonW) were calculated from color Doppler tissue imaging images obtained at apical views in 25 patients with inferior MI and in 13 healthy control subjects. All 25 patients with MI underwent magnetic resonance imaging to assess the infarct status of PM. RESULTS: Compared with the control subjects, patients with MI had significantly lower V of adjacent inferior wall (5.0 +/- 0.8 vs 4.4 +/- 1.1 cm/s, P = .049) and V of posteromedial PM (4.9 +/- 0.8 vs 4.0 +/- 1.2 cm/s, P = .005), and less systolic deformation, as demonstrated by epsilonW (-17 +/- 3 vs -6 +/- 5%, P < .001) and epsilonPM (-24 +/- 5 vs -11 +/- 6%, P < .001). There was a weak positive correlation between epsilonW and epsilonPM (r = 0.393, P = .052) for patients with MI. Magnetic resonance imaging showed total infarct of PM in 14 patients (group A), with the remaining 11 revealing either normal perfusion or partial infarct of PM (group B). Although epsilonW was similar in groups A and B (-5 +/- 5% vs -8 +/- 6%, P = .20), epsilonPM was significantly lower in group B (-7 +/- 4% vs -16 +/- 4%, P = .004). CONCLUSIONS: In patients with inferior wall MI, infarct status of the PM is variable and determines its systolic contractile function, which can be quantified by epsilon measurement using Doppler tissue imaging.
Authors:
Soo-Jin Kang; Eun Young Lee; Jae-Kwan Song; Kyung-Hyun Do; Joon Beom Seo; Tae-Hwan Lim; Jong-Min Song; Duk-Hyun Kang; Young-Hak Kim; Cheol Whan Lee; Myeong-Ki Hong; Seong-Wook Park; Seung-Jung Park
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  18     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-08     Completed Date:  2006-03-31     Revised Date:  2007-11-02    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  815-20     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity / physiology
Coronary Vessels / physiopathology*,  ultrasonography
Echocardiography, Doppler, Color*
Humans
Magnetic Resonance Imaging
Myocardial Infarction / physiopathology*,  ultrasonography
Papillary Muscles / physiopathology*,  ultrasonography
Systole / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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