Document Detail


Assessment of oxidant/anti-oxidant system in newborns and their breast milks.
MedLine Citation:
PMID:  23211119     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract AIM: In this study, it is aimed to investigate total oxidant and anti-oxidant status of newborns and their breast milks.METHODS: Totally, 184 infants who were born in our hospital were included in the study. Study group was divided into two main study groups, including term and preterm groups; main study groups were also divided into two sub-groups, AGA and SGA. TOS and TAC levels were measured in cord blood of all newborns and in mother milks. Groups were statistically compared with each other in terms of TOS, TAC and OSI levels.RESULTS: The study included 92 preterm newborns (Group I) and 92 term newborns (Group II). TOS, TAC and OSI levels were found significantly higher in Group I than Group II (p<0,0001, p=0,17, p<0,0001, respectively ). When sub-groups of Group I and Group II, namely TAGA, TSGA and PAGA and PSGA, were compared with each other. TOS and OSI levels were significantly higher and TAC levels were significantly lower in TSGA group relative to TAGA group (p<0,0001; p=0,001; p<0,0001, respectively). No statistically significant difference was found between Group I and Group II and between sub-groups of Group I and II with regards the TOC, TAC and OSI levels of mother milkCONCLUSION: In preterm newborns and term SGA infants, total oxidant stress is increased and anti-oxidant capacity is low. No significant difference was found between mother milks of preterm and term AGA and SGA infants.
Authors:
Gonca Sandal; Nurdan Uras; Tulin Gokmen; Suna Serife Oguz; Omer Erdeve; Ugur Dilmen
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-4
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Neonatology Department, Zekai Tahir Burak Maternity Teaching Hospital, Altindag Ankara, Turkey.
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