Document Detail

Assessment of occlusive arterial disease of abdominal aorta and lower extremities arteries: value of multidetector CT angiography using an adaptive acquisition method.
MedLine Citation:
PMID:  17899108     Owner:  NLM     Status:  MEDLINE    
We evaluated 16-detector-row CT in the assessment of occlusive peripheral arterial disease (PAD) of the abdominal aorta and lower extremities using an adaptive method of acquisition to optimise arterial enhancement especially for the distal foot arteries. Thirty-four patients underwent transcatheter angiography (TCA) and CT angiography within 15 days. For each patient, table speed and rotation were selected according to the calculated optimal transit time of contrast material obtained after a single bolus test and two dynamic acquisitions at aorta and popliteal arteries. Analysis included image quality and detection of stenosis equal or greater than 50% on a patient basis and on an arterial segment basis. Sensitivity and specificity of CT were calculated with the TCA considered as the standard of reference. CT was conclusive in all segments with no technical failures even in difficult cases with occluded bypasses and aneurysms. On patient-basis analysis, the overall sensitivity and specificity to detect significant stenosis greater than 50% were both 100%. Segmental analysis shows high values of sensitivity and specificity ranging from 91 to 100% and from 81 to 100%, respectively, including distal pedal arteries. Sixteen-detector-row CT angiography using an adaptive acquisition improves the image quality and provides a reliable non-invasive technique to assess occlusive peripheral arterial disease, including distal foot arteries.
T Laswed; E Rizzo; D Guntern; F Doenz; A Denys; P Schnyder; S D Qanadli
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2007-09-26
Journal Detail:
Title:  European radiology     Volume:  18     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-04     Completed Date:  2008-06-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  263-72     Citation Subset:  IM    
Department of Radiology, CHUV, University Hospital of Lausanne, Bugnon 46, 1012 Lausanne, Switzerland.
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MeSH Terms
Aged, 80 and over
Aorta, Abdominal / radiography*
Arterial Occlusive Diseases / diagnosis*
Contrast Media / administration & dosage
Femoral Artery / radiography
Iliac Artery / radiography
Image Processing, Computer-Assisted
Iohexol / diagnostic use
Leg / blood supply*,  radiography*
Middle Aged
Peripheral Vascular Diseases / diagnosis*
Popliteal Artery / radiography
Radiographic Image Enhancement / methods
Reproducibility of Results
Sensitivity and Specificity
Tibial Arteries / radiography
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media; 66108-95-0/Iohexol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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