Document Detail


Assessment of the neutrophil to lymphocyte ratio in young patients with acute coronary syndromes.
MedLine Citation:
PMID:  23760114     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objectives: It is well known that inflammation plays a key role in both initiation and propagation of acute coronary syndrome (ACS). White blood cell (WBC) and its subtypes are an indicator of inflammation in patients with ACS. We aimed to evaluate the WBC and its subtypes in patients aged <45 year with acute coronary syndromes. Study design: We retrospectively analyzed WBC and its subtypes (including neutrophil and lymphocyte) in 84 patients (<45 year) who were admitted to the emergency department for chest pain suggestive of ACS (44 unstable angina pectoris, 40 non-ST-segment elevation myocardial infarction [NSTEMI]), and 40 healthy controls. Results: Hypertension, diabetes mellitus, smoking, and family history were significantly higher in NSTE-ACS patients. Also, LDL levels was significantly higher and HDL levels was significantly lower in NSTE-ACS patients (p=0.041 and p=0.009). The difference in percent of lymphocytes between the groups was significant (p=0.048). N/L ratio was significantly different between all groups and between the NSTEMI and USAP (p<0.001 and p=0.041). Our results demonstrated that hypertension, percent of neutrophils, and N/L ratio was a significant independent predictor of NSTE-ACS (Beta=0.251, 95% CI=0.002-0.523, p=0.048; beta=0.561, 95% CI=0.008-0.137, p=0.028 and beta=0.260, 95% CI=0.042-0.438, p=0.018, respectively). Conclusion: N/L was found to be elevated in young patients with NSTE-ACS compared with control group. The inflammation assessed using WBC and its subtypes may be more important in young NSTE-ACS patients.
Authors:
Serkan Oztürk; Alim Erdem; Mehmet Fatih Ozlü; Selim Ayhan; Kemalettin Erdem; Mehmet Ozyaşar; Yusuf Aslantaş; Mehmet Yazıcı
Related Documents :
12077684 - Elastase release following myocardial ischemia during extracorporeal circulation (ecc) ...
2091374 - Neutrophil and lymphocyte locomotion in patients with selective iga deficiency.
24068784 - Encephalitis and gabab receptor antibodies: novel findings in a new case series of 20 p...
23801844 - Psychometrics of chronic liver disease questionnaire in chinese chronic hepatitis b pat...
15232434 - A retrospective radiographic review of hemophilic shoulder arthropathy.
23208014 - The challenge of antiplatelet therapy in patients with atrial fibrillation and heart fa...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır     Volume:  41     ISSN:  1016-5169     ISO Abbreviation:  Turk Kardiyol Dern Ars     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426239     Medline TA:  Turk Kardiyol Dern Ars     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  284-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Abant İzzet Baysal University Faculty of Medicine, Bolu, Turkey. drserkan69@hotmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Serum gamma-glutamyltransferase and the burden of atherosclerosis in patients with acute coronary sy...
Next Document:  The serum pentraxin-3 is elevated in patients with cardiac syndrome X.