| Assessment of the mechanical properties of coronary arteries using intravascular ultrasound: an in vivo study. | |
| | |
MedLine Citation:
|
PMID: 10517378 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The pressure-area relation of coronary arteries provides important information about the mechanical properties of these vessels. In human subjects methodological limitations have precluded measurement of instantaneous compliance and coronary stress in vivo. The purpose of this study was to assess a new method for measuring instantaneous values of coronary artery compliance and wall stress utilizing simultaneously acquired pressure and intravascular ultrasound measurements of vessel area. Ten subjects with coronary artery disease had intravascular ultrasound studies of the proximal left anterior descending or circumflex coronary arteries. Coronary luminal area was measured with a 30-MHz (3F or 3.5F) intravascular ultrasound catheter and simultaneous coronary pressure measured with a 2F micromanometer-tipped catheter. Using this technique the nonlinear pressure-area relation and mean circumferential wall stress were determined over the physiological pressure range. Coronary artery compliance at 100 mmHg ranged from 0.010 to 0.052 mm2/mmHg (mean +/- SD, 0.020+/-0.012 mm2/mmHg). Peak systolic circumferential stress ranged from 0.52 to 2.03 x 10(6) dyn/cm2 (1.09+/-0.42 x 10(6) dyn/cm2). This study describes a new method of determining coronary artery mechanical properties over the physiological pressure range. This technique may be useful in further studies of coronary artery mechanics. |
| | |
Authors:
|
M J Williams; R A Stewart; C J Low; G T Wilkins |
Related Documents
:
|
1391498 - Effects of modified hemoglobin solutions on the isolated rabbit heart. 15550728 - Coronary pressure notch: an early non-hyperemic visual indicator of the physiologic sig... 8719388 - Translesional pressure and flow velocity after thrombolysis: assessment of suboptimal a... 7251868 - Comparison of acute alterations in left ventricular relaxation and diastolic chamber st... 8089828 - Evaluation of the accuracy and reproducibility of ambulatory blood pressure monitoring ... 15501108 - Resuscitation with a blood substitute causes vasoconstriction without nitric oxide scav... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: International journal of cardiac imaging Volume: 15 ISSN: 0167-9899 ISO Abbreviation: Int J Card Imaging Publication Date: 1999 Aug |
Date Detail:
|
Created Date: 1999-11-23 Completed Date: 1999-11-23 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8600426 Medline TA: Int J Card Imaging Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 287-94 Citation Subset: IM |
Affiliation:
|
Department of Medicine, University of Otago, Dunedin, New Zealand. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Compliance Coronary Disease / physiopathology, ultrasonography* Coronary Vessels / physiopathology, ultrasonography* Female Humans Male Middle Aged Ultrasonography, Interventional / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Echocardiographic and Doppler study of patients with heatstroke and heat exhaustion.
Next Document: Does remodeling occur in the diseased human saphenous vein bypass grafts? An intravascular ultrasoun...