Document Detail

Assessment of lower limb ischemia with measurement of skin perfusion pressure in patients on hemodialysis.
MedLine Citation:
PMID:  17498001     Owner:  NLM     Status:  MEDLINE    
Measurement of skin perfusion pressure (SPP) using laser Doppler has become available for the assessment of peripheral arterial disease. We studied whether measurements of SPP can be used to identify hemodialyzed patients with peripheral arterial disease by comparing it with measurements of the ankle brachial pressure index (ABI). The ABI at rest and the SPP in the foot were measured in 59 Japanese hemodialyzed patients (118 limbs). Twenty-one patients had diabetes mellitus. Five had intermittent claudication; however, 20 patients were accompanied by other exertional leg symptoms. The SPP could not be measured in three limbs because of involuntary movement due to previous stroke or restless leg syndrome. The SPP was correlated with the ABI. Depending upon these results of the ABI, the 114 limbs from which both the ABI and the SPP could measured were divided into three groups: (A) ABI > or = 1.3, (B) 0.9 < or = ABI < 1.3, and (C) ABI < 0.9. The average SPP of group C was significantly decreased among the three groups. All subjects of the three groups were divided into an extra two groups according to the presence of diabetes (non-diabetes groups, -I; diabetes groups, -II). The average SPP of group B-II was significantly decreased compared with those of group B-I. The SPP measurement is a noninvasive, useful screening method for limb ischemia that can be applied to exercise tolerance limited patients. The SPP measurements are expected to be useful for the evaluation of limb ischemia in hemodialyzed patients at risk.
Masaru Shimazaki; Takayuki Matsuki; Kazuaki Yamauchi; Michihiro Iwata; Hiroshi Takahashi; Satoshi Genda; Junichi Ohata; Yuichi Nakamura; Yoshie Inaba; Satoru Yokouchi; Tsuyoshi Kikuiri; Takeshi Ashie
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy     Volume:  11     ISSN:  1744-9979     ISO Abbreviation:  Ther Apher Dial     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-14     Completed Date:  2007-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101181252     Medline TA:  Ther Apher Dial     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  196-201     Citation Subset:  IM    
Division of Hemodialysis, Shin-Nittetsu Muroran General Hospital, Muroran, Japan.
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MeSH Terms
Aged, 80 and over
Brachial Artery / ultrasonography*
Diabetes Complications
Ischemia / ultrasonography*
Laser-Doppler Flowmetry
Middle Aged
Peripheral Vascular Diseases / epidemiology,  etiology,  ultrasonography*
Renal Dialysis / adverse effects*
Comment In:
Nat Clin Pract Nephrol. 2007 Nov;3(11):598-9   [PMID:  17876352 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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