| Assessment of left ventricular systolic synchronization in patients with chronic kidney disease and narrow QRS complexes. | |
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MedLine Citation:
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PMID: 19438694 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The evidence of structural and functional cardiac abnormalities has been demonstrated by echocardiography in patients with chronic kidney disease (CKD). This study investigated whether left ventricular (LV) asynchrony is present in patients with CKD and normal QRS duration. METHODS: Tissue synchronization imaging (TSI) was performed in 25 (56 +/- 14 years) patients with CKD and narrow QRS complexes and 25 (51 +/- 12 years) control subjects. LV asynchrony was identified on TSI images and the time to regional peak systolic velocity (Ts) in LV was measured by the six-basal-six-midsegmental model. Four TSI parameters of systolic asynchrony were computed when Ts was measured in ejection phase. RESULTS: The standard deviation of Ts of 12 LV segments (33.6 +/- 17.8 vs 16.7 +/- 10 ms, P = 0.0001), standard deviation of Ts of the six basal LV segments (30 +/- 20 vs 17.6 +/- 9.6 ms, P = 0.008), maximal difference in Ts between any two of the 12 LV segments (102 +/- 45 vs 54 +/- 32 ms, P = 0.0001), and maximal difference in Ts between any two of the six basal LV segments (78 +/- 50 vs 46 +/- 22 ms, P = 0.007) were prolonged in patients with CKD compared with controls. The prevalence of LV systolic asynchrony was significantly higher in patients with CKD compared with controls (44% vs 12%, P = 0.01). The standard deviation of Ts of 12 LV segments were significantly associated with LV diameters, LV volumes, LV mass, blood pressure levels, and renal functions in univariate analysis. CONCLUSION: The results of this study indicate that LV systolic asynchrony may develop in patients with CKD. |
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Authors:
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Omer Gedikli; Merih Baykan; Kubra Kaynar; Gulsum Ozkan; Levent Korkmaz; Serkan Ozturk; Ismet Durmus; Sahin Kaplan; Sukru Celik |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Echocardiography (Mount Kisco, N.Y.) Volume: 26 ISSN: 1540-8175 ISO Abbreviation: Echocardiography Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-14 Completed Date: 2009-07-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: United States |
Other Details:
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Languages: eng Pagination: 528-33 Citation Subset: IM |
Affiliation:
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KTU Faculty of Medicine, Department of Cardiology, Trabzon, Turkey. omergedikli@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Echocardiography* Electrocardiography* Female Humans Kidney Failure, Chronic / complications*, diagnosis* Male Middle Aged Reproducibility of Results Sensitivity and Specificity Ventricular Dysfunction, Left / diagnosis*, etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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