Document Detail

Assessment of left ventricular myocardial scar in infiltrative and non-ischemic cardiac diseases by free breathing three dimensional phase sensitive inversion recovery (PSIR) TurboFLASH.
MedLine Citation:
PMID:  20499279     Owner:  NLM     Status:  In-Data-Review    
The purpose of this study was to compare a navigator gated free breathing 3D Phase Sensitive Inversion Recovery (PSIR) TurboFLASH to an established 2D PSIR TurboFLASH method for detecting myocardial late gadolinium hyperenhanced lesions caused by infiltrative and non-ischemic cardiomyopathy. Under an IRB approved protocol; patients with suspected non-ischemic infiltrative myocardial heart disease were examined on a 1.5T MR scanner for late enhancement after the administration of gadolinium using a segmented 2D PSIR TurboFLASH sequence followed by a navigator-gated 3D PSIR TurboFLASH sequence. Two independent readers analyzed image quality using a four point Likert scale for qualitative analysis (0 = poor, non diagnostic; 1 = fair, diagnostic may be impaired; 2 = good, some artifacts but not interfering in diagnostics, 3 = excellent, no artifacts) and also reported presence or absence of scar. Detected scars were classified based on area and location and also compared quantitatively in volume. Twenty-seven patients were scanned using both protocols. Image quality score did not differ significantly (p = 0.358, Wilcoxon signed rank test) for both technique. Scars were detected in 24 patients. Larger numbers of hyperenhanced scars were detected with 3D PSIR (200) compared to 2D PSIR (167) and scar volume were significant larger in 3D PSIR (p = 0.004). The mean scar volume over all cases was 49.95 cm(3) for 2D PSIR and 70.02 cm(3) for 3D PSIR. The navigator gated free breathing 3D PSIR approach is a suitable method for detecting myocardial late gadolinium hyperenhanced lesions caused by non-ischemic cardiomyopathy due to its complete isotropic coverage of the left ventricle, improving detection of scar lesions compared to 2D PSIR imaging.
Aya Kino; Aoife N Keeling; Cormac T Farrelly; John J Sheehan; Amir H Davarpanah; Peter J Weele; Sven Zuehldorff; James C Carr
Related Documents :
1476269 - Diagnosis of coronary artery disease with tc 99m-methoxy isobutyl isonitrile and transe...
830219 - The specificity of the diffuse pattern of cardiac uptake in myocardial infarction imagi...
8111669 - Asymptomatic heterotopic thyroid tumour in the right ventricular infundibulum.
618619 - The clinical estimation of acute myocardial infarct size with 99mtechnetium pyrophospha...
22449849 - Cardiac regeneration.
9169569 - Therapeutic effect of co-enzyme q10 on idiopathic dilated cardiomyopathy: assessment by...
20579749 - Oestradiol supplement minimises coronary occlusion-induced myocardial infarction and ve...
15246899 - Evaluation of a high-dose dexamethasone-eluting stent.
9035699 - Assessment of fetal pulmonic stenosis by ultrasonography.
Publication Detail:
Type:  Journal Article     Date:  2010-05-26
Journal Detail:
Title:  The international journal of cardiovascular imaging     Volume:  27     ISSN:  1875-8312     ISO Abbreviation:  Int J Cardiovasc Imaging     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-05-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100969716     Medline TA:  Int J Cardiovasc Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  527-37     Citation Subset:  IM    
Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  National study of an early parenting intervention: implementation differences on parent and child ou...
Next Document:  Higher expression of the heterogeneous nuclear ribonucleoprotein k in melanoma.