Document Detail

Assessment of left ventricular diastolic function using 4-dimensional phase-contrast cardiac magnetic resonance.
MedLine Citation:
PMID:  21245695     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVES: : Phase-contrast magnetic resonance imaging can potentially assess the dynamics of left ventricular (LV) early diastolic filling.
METHODS: : Fifteen participants underwent phase-contrast magnetic resonance imaging on a 1.5-T whole-body Avanto scanner (Siemens Healthcare, Erlangen, Germany). Left ventricular intracavitary velocities were measured in 3 orthogonal directions. Imaging parameters included a repetition time of 92.45 milliseconds, an echo time of 2.88 milliseconds, a flip angle of 30 degrees, and a velocity-encoding range of 100 to 150 cm/s.
RESULTS: : The color vector analysis provided a visual assessment of LV diastolic flow. In normal subjects, there was rapid organized early diastolic flow that extended from the mitral valve to the LV apex. In patients with LV diastolic dysfunction, organized high-velocity flow stopped in the mid-left ventricle.
CONCLUSIONS: : Four-dimensional phase-contrast cardiovascular magnetic resonance can differentiate between normal and abnormal diastolic flow propagation within the left ventricle.
Rahul Kumar; John Charonko; W Gregory Hundley; Craig A Hamilton; Kelley C Stewart; Gary R McNeal; Pavlos P Vlachos; William C Little
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  35     ISSN:  1532-3145     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2011-01-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  108-12     Citation Subset:  IM    
From the *Section of Cardiology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC; †Department of Mechanical Engineering, School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, Virginia; ‡Department of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC; and §Siemens Healthcare, Cardiovascular Magnetic Resonance Research and Development, Chicago, IL.
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