| Assessment of the intratesticular resistive index by colour Doppler ultrasonography measurements as a predictor of spermatogenesis. | |
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MedLine Citation:
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PMID: 18190642 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the value of the resistive index (RI) of intratesticular arteries, and to establish diagnostic criteria for normal and pathological sperm counts on the basis of quantitative colour Doppler ultrasonography (CDUS), as the assessment of the testicular RI is widely used to measure intratesticular blood flow. PATIENTS AND METHODS: In all, 160 men (aged 22-43 years, 320 testicles) were prospectively investigated; 80 had a normal and 80 a pathological sperm count, the latter having mild oligoasthenozoospermia. The RI was measured using a high-frequency Doppler ultrasound probe (14 MHz), three times on each testicle at an intratesticular artery in the upper, middle and lower testicular pole. The testicular volume was also measured by US. The RI values were compared between patients with normal and pathological sperm counts, and were compared statistically with testicular volumes. In addition, blood samples were obtained for DNA extraction, chromosome analysis and hormonal evaluations. RESULTS: Patients with normal sperm counts had a mean (sd) RI of 0.54 (0.05) and a mean testicular volume of 18.7 (5.2) mL, the respective values in those with pathological sperm counts were 0.68 (0.06) and 16.8 (6.0) mL, with a significantly greater RI in the latter (P < 0.001), but with no statistically significant difference in testicular volume between the groups (P > 0.05). CONCLUSION: These preliminary data suggest that an RI of >0.6 might be suggestive of a pathological sperm count in andrological patients. The intratesticular RI as measured by CDUS seems to be a reliable indicator for routine clinical use to identify subfertile men. |
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Authors:
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Germar-Michael Pinggera; Michael Mitterberger; Georg Bartsch; Hannes Strasser; Johannes Gradl; Friedrich Aigner; Leo Pallwein; Ferdinand Frauscher |
Publication Detail:
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Type: Journal Article Date: 2008-01-08 |
Journal Detail:
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Title: BJU international Volume: 101 ISSN: 1464-410X ISO Abbreviation: BJU Int. Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-02-22 Completed Date: 2008-03-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100886721 Medline TA: BJU Int Country: England |
Other Details:
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Languages: eng Pagination: 722-6 Citation Subset: IM |
Affiliation:
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Department of Urology, Medical University Innsbruck, Austria. germar.pinggera@uki.at |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Humans Ischemia / complications, ultrasonography Male Oligospermia / physiopathology, ultrasonography* Prospective Studies Severity of Illness Index Sperm Count / methods Spermatogenesis / physiology* Testis / blood supply, physiopathology, ultrasonography* Testosterone / blood Ultrasonography, Doppler, Color* |
| Chemical | |
Reg. No./Substance:
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58-22-0/Testosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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