Document Detail

Assessment of intermittent claudication by quantitation of exercise-induced microalbuminuria.
MedLine Citation:
PMID:  2279570     Owner:  NLM     Status:  MEDLINE    
Urinary albumin excretion rates, expressed as albumin-creatinine ratios (ACR, mg/mmol) were measured before and after exercise in 23 claudicants and 10 controls. The mean (range) resting ACRs in the claudicants and controls were 4.42 (0.2-34.6) and 0.77 (0.3-2.8) respectively (P less than 0.001). ACR increased after exercise by a mean of 153% in claudicants to 9.7 (0.2-48.1; P less than 0.001) with no change in controls, 0.79 (0.2-2.1). In patients with claudication there was a positive correlation between ankle pressure recovery time and the relative increase in ACR after exercise (r = 0.64, P less than 0.01). The post-exercise increase in ACR was reduced in all nine patients who underwent bypass surgery. Measurement of ACR after exercise appears to be related to severity of muscle ischaemia and may assist in the assessment of patients with intermittent claudication.
N C Hickey; C P Shearman; P Gosling; M H Simms
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of vascular surgery     Volume:  4     ISSN:  0950-821X     ISO Abbreviation:  Eur J Vasc Surg     Publication Date:  1990 Dec 
Date Detail:
Created Date:  1991-03-08     Completed Date:  1991-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8709440     Medline TA:  Eur J Vasc Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  603-6     Citation Subset:  IM    
Department of Surgery, Selly Oak Hospital, Birmingham, U.K.
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MeSH Terms
Albuminuria / etiology*
Exercise / physiology*
Exercise Test
Intermittent Claudication / diagnosis,  urine*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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