Document Detail

Assessment of intermittent claudication by means of the transcutaneous oxygen tension exercise profile.
MedLine Citation:
PMID:  2397779     Owner:  NLM     Status:  MEDLINE    
Transcutaneous oxygen tension was measured simultaneously on both feet during exercise (TcpO2 exercise profile) in patients with claudication. The following groups were studied: 1) 21 control subjects; 2) 25 patients with bilateral claudication of whom eight had unilateral predominance; 3) 40 patients with unilateral claudication. The control group showed no significant decrease in TcpO2 during exercise. Patients with bilateral claudication and unilateral predominance showed a significant decrease in the TcpO2 exercise profile of both feet (P less than 0.05), the decrease in the more affected leg being significantly greater than that of the less affected leg (P less than 0.05). In patients without unilateral predominance of claudication there was a slight, yet significant decrease in TcpO2 of both legs. Patients with unilateral claudication were classified into three groups based on a constant work load of 50 W, which provoked typical leg pain during exercise (group I: 0-2 min; group II: 2-4 min; group III: greater than 4 min). The decrease in the TcpO2 exercise profile was always significant on the symptomatic leg. In the asymptomatic leg TcpO2 did not decrease. The changes in TcpO2 relative to values at rest of the symptomatic leg showed significant differences after 1 min in groups I, II, and III (P less than 0.05). In conclusion, the TcpO2 exercise profile appears to be a suitable objective method by which the peripheral arterial insufficiency during exercise in patients with intermittent claudication can be quantified.
J F Larsen; K S Christensen; K Egeblad
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of vascular surgery     Volume:  4     ISSN:  0950-821X     ISO Abbreviation:  Eur J Vasc Surg     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-10-16     Completed Date:  1990-10-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8709440     Medline TA:  Eur J Vasc Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  409-12     Citation Subset:  IM    
Department of Thoracic and Vascular Surgery, Aalborg Sygehus, Denmark.
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MeSH Terms
Blood Gas Monitoring, Transcutaneous*
Exercise Test*
Intermittent Claudication / physiopathology*
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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