| Assessment of the hemorheological profile of koala and echidna. | |
| | |
MedLine Citation:
|
PMID: 20138490 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Koala, a marsupial, and echidna, a monotreme, are mammals native to Australia. Blood viscosity (62.5-1250s(-1)), red blood cell (RBC) deformability, RBC aggregation, aggregability and surface charge, and hematological parameters were measured in blood samples from six koalas and six echidnas and compared to adult human blood. Koala had the largest RBC mean cell volume (107.7+/-2.6fl) compared to echidna (81.3+/-2.6fl) and humans (88.4+/-1.2fl). Echidna blood exhibited the highest viscosity over the entire range of shear rates. Echidna RBC were significantly less deformable than koala RBC but more deformable than human RBC. Echidna RBC had significantly lower aggregability (i.e., aggregation in standardized dextran medium) than koala or human RBC, while aggregation in autologous plasma was similar for the three species. Erythrocyte surface charge as indexed by RBC electrophoretic mobility was similar for human and echidna cells but was 40% lower for koala RBC. Data obtained during this preliminary study indicate that koala and echidna have distinct hemorheological characteristics; investigation of these properties may reveal patterns relevant to specific behavioral and physiological features of these animals. |
| | |
Authors:
|
Oguz K Baskurt; Sonya Marshall-Gradisnik; Michael Pyne; Michael Simmonds; Ekua Brenu; Rhys Christy; Herbert J Meiselman |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Zoology (Jena, Germany) Volume: 113 ISSN: 1873-2720 ISO Abbreviation: Zoology (Jena) Publication Date: 2010 Mar |
Date Detail:
|
Created Date: 2010-04-12 Completed Date: 2010-07-13 Revised Date: 2011-07-25 |
Medline Journal Info:
|
Nlm Unique ID: 9435608 Medline TA: Zoology (Jena) Country: Germany |
Other Details:
|
Languages: eng Pagination: 110-7 Citation Subset: IM |
Affiliation:
|
Department of Physiology, Faculty of Medicine, Akdeniz University, Dumlupinar Blv., Antalya 07058, Turkey. baskurt@akdeniz.edu.tr <baskurt@akdeniz.edu.tr> |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Echidna / blood* Erythrocytes / physiology Female Hematologic Tests Hemorheology* Humans Male Phascolarctidae / blood* |
| Grant Support | |
ID/Acronym/Agency:
|
HL 015722/HL/NHLBI NIH HHS; HL 070595/HL/NHLBI NIH HHS; HL 090511/HL/NHLBI NIH HHS; R01 HL015722-31/HL/NHLBI NIH HHS; U54 HL070595-059002/HL/NHLBI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dentin abnormalities in cheek teeth of wild red deer and roe deer from a fluoride-polluted area in C...
Next Document: Preselection of patients at risk for COPD by two simple screening questions.