Document Detail

Assessment of healing kinetics through true color image processing.
MedLine Citation:
PMID:  18218389     Owner:  NLM     Status:  In-Data-Review    
A quantitative method of skin healing assessment using true color image processing is presented. The method was developed during a clinical trial using healthy volunteers, the goal of which was to study a drug for accelerating healing. Photographic images of the skin were sequentially acquired between day 1 and day 12 after pure painless epidermal wounds. The images were digitized in controlled conditions using a color video camera connected to a computer system. A color threshold based segmentation was developed to provide an operator-independent delineation of the wound. Two healing indexes were built measuring, the wound area and the wound color. The method was implemented in a software system allowing a fully automated determination of the healing indexes. The method provides a new quantitative global assessment of healing kinetics. It is noninvasive and well suited for multicentric clinical trials.
M Herbin; F X Bon; A Venot; F Jeanlouis; M L Dubertret; L Dubertret; G Strauch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  IEEE transactions on medical imaging     Volume:  12     ISSN:  0278-0062     ISO Abbreviation:  IEEE Trans Med Imaging     Publication Date:  1993  
Date Detail:
Created Date:  2008-01-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8310780     Medline TA:  IEEE Trans Med Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  39-43     Citation Subset:  -    
ECLIMED, Hoptial Cochin, Paris.
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