| Assessment of haemolytic and thromboembolic potentials--from CFD studies of Starr-Edwards cardiac valve prostheses. | |
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MedLine Citation:
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PMID: 2604624 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Quantitative assessments of haemolysis, thromboembolism and endothelial damage are established using computational fluid dynamics and documented threshold values. The régime studied was steady forward (systolic) flow through a fully open Starr-Edwards model 1260 ball valve, in an aortic shaped chamber. Modelling was carried out using finite difference techniques for turbulent, Newtonian flow. Haemolysis was not predicted "in-bulk", but a haemolytic potential as high as 30% was suggested at prosthetic surfaces. Also a 10% thromboembolic potential and a 6% potential for endothelium damage were noted. |
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Authors:
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G D Tansley; J Mazumdar; B J Noye; I H Craig; K Thalassoudis |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Australasian physical & engineering sciences in medicine / supported by the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicine Volume: 12 ISSN: 0158-9938 ISO Abbreviation: Australas Phys Eng Sci Med Publication Date: 1989 Sep |
Date Detail:
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Created Date: 1990-02-06 Completed Date: 1990-02-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8208130 Medline TA: Australas Phys Eng Sci Med Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 121-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aortic Valve Endothelium, Vascular / injuries* Heart Valve Prosthesis / adverse effects* Hemolysis* Humans Mathematics Models, Statistical* Reference Values Thromboembolism / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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