Document Detail


Assessment of gastric secretory function by 24-hour pH-metry in patients with hepatic cirrhosis due to HBV infection, before and after non-shunt type Sugiura procedure.
MedLine Citation:
PMID:  15156614     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Assessment of gastric secretory function by 24-hour pH-metry in patients with hepatic cirrhosis due to HBV infection, before and after non-shunt type Sugiura procedure. AIM OF THE STUDY: Advanced chronic hepatopathies are very often accompanied by pathologic changes in the stomach as well as functional disturbances affecting the upper gastrointestinal tract. They include ulceration, erosions, and congestive (portal) gastropathy, reported with increasing frequency. Some of these patients undergo surgical treatment to prevent recurrent esophageal variceal bleeding. Because of considerable differences in gastric hydrochloric acid secretion, its assessment was attempted in patients with hepatic cirrhosis and portal hypertension before (group II) and after (group III) non-shunt type surgical procedure. MATERIAL/METHODS: The study was carried out in two groups of patients, consisting of 11 patients each, and a control group of 15 healthy volunteers. Subjects over 65 years of age, with concurrent chronic conditions, history of surgical procedures (except for Sugiura procedure) and treated with drugs affecting gastric secretion were excluded from the study. All the subjects qualified for the study underwent pH-metry with a DL70 pH-meter equipped with a glass electrode. Median pH (Me) and mean pH values (arithmetic mean, AM) from 24 h were used in analysis. RESULTS: The following results were obtained--in the control group Me 1.57, AM. 1.97; in group II Me 2.04, AM 2.53. In the group of patients after Sugiura procedure Me was 2.83 and AM 3.12. No statistically significant differences in gastric secretion were found between the studied groups in statistical analysis using Cochran, Cox and Student-t tests. CONCLUSION: There are no statistically significant differences in gastric secretion determined by 24-hour pH-metry in patients with hepatic cirrhosis due to HBV infection and portal hypertension before and after non-shunt type Sugiura procedure.
Authors:
Marcin Orłowski
Related Documents :
18094914 - Transcatheter closure of patent ductus arteriosus among native high-altitude habitants.
9794904 - Portosystemic hepatic encephalopathy after transjugular intrahepatic portosystemic shun...
1994594 - Surgical treatment of severe postshunt hepatic encephalopathy.
12181684 - Five years experience with gravitational shunts in chronic hydrocephalus of adults.
3398544 - Acute liver dysfunction after modified fontan operation for complex cardiac lesions. an...
20514264 - A comparison of arthroscopically assisted single and double bundle tibial inlay reconst...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical science monitor : international medical journal of experimental and clinical research     Volume:  9 Suppl 3     ISSN:  1234-1010     ISO Abbreviation:  Med. Sci. Monit.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2004-05-25     Completed Date:  2004-06-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9609063     Medline TA:  Med Sci Monit     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  55-9     Citation Subset:  IM    
Affiliation:
Department of Infectious Diseases, Medical University of Gdańsk, Gdańsk, Poland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Case-Control Studies
Female
Gastric Mucosa / secretion*
Hepatitis B / complications*
Humans
Hydrogen-Ion Concentration*
Liver Cirrhosis / etiology,  pathology*
Male
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Autoimmune hepatitis in the material of Department and Regional Hospital of Infectious Diseases in G...
Next Document:  Assessment of correlation between histopathologic changes of gastric mucosa according to Whitehead's...