Document Detail

Assessment of gastric accommodation: overview and evaluation of current methods.
MedLine Citation:
PMID:  15198649     Owner:  NLM     Status:  MEDLINE    
Gastric accommodation is considered important in the pathophysiology of several upper gastrointestinal disorders including functional dyspepsia. The gold standard for its measurement is the barostat-balloon study which requires intubation. The aim was explore the reliability and performance characteristics of the techniques proposed for measurement of gastric accommodation. We undertook a literature search using MEDLINE with a broad range of key words. The accommodation reflex and its control are briefly described, based on human data. The performance characteristics of the intragastric barostat, transabdominal ultrasound, magnetic resonance imaging, single photon emission computed tomography, and satiation drinking tests are described. For each technique, we summarize the following: principle, validation studies, advantages, disadvantages, and potential applications. Three-dimensional methods to measure gastric volume non-invasively are promising and among the best validated to date. Simpler techniques would be of considerable appeal for clinical and research studies, but further validation is necessary before satiation drinking tests can be used as surrogates for more sophisticated measurements of gastric accommodation.
H U De Schepper; F Cremonini; D Chitkara; M Camilleri
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society     Volume:  16     ISSN:  1350-1925     ISO Abbreviation:  Neurogastroenterol. Motil.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-16     Completed Date:  2004-08-12     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9432572     Medline TA:  Neurogastroenterol Motil     Country:  England    
Other Details:
Languages:  eng     Pagination:  275-85     Citation Subset:  IM    
Clinical Enteric Neuroscience Translational and Epidemiological Research Program, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
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MeSH Terms
Diagnostic Imaging* / methods
Dyspepsia / diagnosis*
Gastrointestinal Motility / physiology*
Magnetic Resonance Imaging
Manometry* / methods
Muscle Relaxation / physiology
Muscle, Smooth / physiology
Stomach / physiology*
Tomography, Emission-Computed, Single-Photon
Grant Support
Comment In:
Neurogastroenterol Motil. 2004 Jun;16(3):271-3   [PMID:  15198648 ]
Neurogastroenterol Motil. 2005 Feb;17(1):155; author reply 155-6   [PMID:  15670276 ]

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