| Assessment of esophageal motor function using combined multichannel intraluminal impedance and manometry in healthy volunteers: a single-center study in Taiwan. | |
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MedLine Citation:
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PMID: 17608849 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Combined multichannel intraluminal impedance and manometry (MII-EM) allow simultaneous measurement of both pressure and bolus transit. The aim of this study was to establish normative data in Chinese subjects for combined MII-EM and to correlate liquid and viscous bolus transit by impedance with esophageal contractions by manometry. METHODS: Eighteen normal volunteers (six women and 12 men; mean age 24 years, range 19-36 years) underwent combined MII-EM with a catheter containing four impedance-measuring segments and five solid-state pressure transducers. Each subject received 10 liquid and 10 viscous material swallows of 5 mL each. Tracings were analyzed for bolus presence time, total bolus transit time, contraction amplitude, duration, and onset velocity. RESULTS: A total of 180 liquid and viscous swallow responses were analyzed. In all, 98.4% percent of manometrically normal liquid and 97.7% of manometrically normal viscous swallows had complete bolus transit by impedance. More than half (56.3%) of manometrically ineffective liquid and 50% of ineffective viscous swallows had complete bolus transit. Nearly 90% of normal individuals had at least 70% complete liquid bolus transit while more than 90% of normal individuals had at least 70% complete viscous bolus transit. CONCLUSIONS: This study establishes normative data for combined MII-EM in a healthy Chinese population. These data will help provide impedance application in esophageal function testing with a reference range that could be utilized by future studies or clinical practices involving Chinese subjects. |
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Authors:
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Chien-Lin Chen; Chih-Hsun Yi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of gastroenterology and hepatology Volume: 22 ISSN: 0815-9319 ISO Abbreviation: J. Gastroenterol. Hepatol. Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-07-04 Completed Date: 2007-10-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607909 Medline TA: J Gastroenterol Hepatol Country: Australia |
Other Details:
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Languages: eng Pagination: 1039-43 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology and Hepatology, Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan. harry.clchen@msa.hinet.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Electric Impedance Esophagus / physiology* Female Humans Male Manometry Reference Values Taiwan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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