Document Detail


Assessment of disease activity and quality of life in systemic lupus erythematosus - New aspects.
MedLine Citation:
PMID:  19591777     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Outcomes in systemic lupus erythematosus (SLE) can be described in three domains: disease activity, accumulated damage and health-related quality of life (HRQoL). Over the past decade, our understanding and perception of SLE have changed considerably. Gastrointestinal and ophthalmic manifestations have increasingly been recognised, and they are associated with significant morbidity and mortality. Furthermore, it has been realised that there is a deficiency in using generic scales (such as the short form-36 (SF-36)) to assess HRQoL in patients with SLE as they fail to identify issues that are important to patients. As a result, SLE-specific measures of HRQoL have been developed recently. This article looks at the recent updates and changes in the standardised assessment of disease activity and HRQoL in SLE.
Authors:
Chee-Seng Yee; Kathleen McElhone; Lee-Suan Teh; Caroline Gordon
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical rheumatology     Volume:  23     ISSN:  1532-1770     ISO Abbreviation:  Best Pract Res Clin Rheumatol     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-13     Completed Date:  2009-10-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101121149     Medline TA:  Best Pract Res Clin Rheumatol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  457-67     Citation Subset:  IM    
Affiliation:
Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK. csyee@ymail.com
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MeSH Terms
Descriptor/Qualifier:
Humans
Lupus Erythematosus, Systemic / complications,  diagnosis*
Quality of Life*
Sensitivity and Specificity
Severity of Illness Index*

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