Document Detail

Assessment of dioxins in foods from animal origins.
MedLine Citation:
PMID:  9464895     Owner:  NLM     Status:  MEDLINE    
Dioxin is the common name for 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD) but is also used for the structurally and chemically related polychlorinated dibenzo-para-dioxins (PCDD), dibenzofurans (PCDF), and the coplanar polychlorinated biphenyls (PCB). There are 75 PCDD congeners, 135 PCDF, and 209 PCB. Seven PCDD and 10 PCDF with substitutions at the 2,3,7, and 8 positions are considered toxic, and 11 PCB have dioxin-like toxicity. The majority of toxic dioxin is and(or) has been derived from industrial chlorination processes, incineration of municipal waste, and production of certain herbicides. The potential for health risks due to the cancer-promoting, immunomodulating, and teratogenic activities of dioxins in rodents has raised concerns over their presence in the human food chain. The lipophilic nature of dioxins results in higher concentrations in the fat of animal and fish products, and their excretion via milk secretion in dairy cattle may result in relatively high concentrations of dioxin contamination in high-fat dairy products. Surface contamination of plant foods and soil due to deposition of atmospheric emissions may also be a significant direct source of dioxin ingestion for livestock and thereby an indirect source of dioxin for humans. Despite numerous epidemiological studies, dioxin has not been conclusively determined to be problematic for humans. Certain management practices such as trimming fat from meat, consuming low-fat dairy products, and simply cooking food can substantially decrease exposure to dioxin compounds.
R A Roeder; M J Garber; G T Schelling
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of animal science     Volume:  76     ISSN:  0021-8812     ISO Abbreviation:  J. Anim. Sci.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-03-11     Completed Date:  1998-03-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8003002     Medline TA:  J Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  142-51     Citation Subset:  IM    
Department of Animal and Veterinary Science, University of Idaho, Moscow 83844-2330, USA.
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MeSH Terms
Benzofurans / analysis,  toxicity
Dioxins / analysis*,  toxicity
Fish Products / analysis
Food Contamination*
Meat / analysis
Milk / chemistry
Polychlorinated Biphenyls / analysis,  toxicity
Polymers / analysis,  toxicity
Risk Assessment
United States
United States Environmental Protection Agency
Reg. No./Substance:
0/Benzofurans; 0/Dioxins; 0/Polychlorinated Biphenyls; 0/Polymers; 0/polychlorodibenzofuran

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