Document Detail

Assessment of dietary isoflavone intake among middle-aged Chinese men.
MedLine Citation:
PMID:  17374669     Owner:  NLM     Status:  MEDLINE    
We evaluated the reproducibility and validity of the FFQ used in the Shanghai Men's Health Study (SMHS) for assessing dietary isoflavone intake, using multiple 24-h dietary recalls (24-HDR) and urinary isoflavones as the reference criteria, with data from the dietary validation study of the SMHS. A total of 196 study subjects completed the 24-HDR and 2 FFQ and donated a quarterly spot urine sample during the 1-y study period. Levels of urinary isoflavones were measured in a random sample of 48 study participants. The correlation coefficient between the 2 FFQ administered 1 y apart was 0.50 for soy protein intake and ranged from 0.50 to 0.51 for isoflavone intake. The correlations of isoflavone intake from the second FFQ with those from the multiple 24-HDR ranged from 0.38 (genistein) to 0.44 (glycitein), and the correlations with urinary isoflavone levels were 0.48 for total isoflavones, 0.44 for daidzein, 0.42 for genistein, and 0.54 for glycitein. The intraclass correlation coefficients for the 4 spot urine samples were 0.36, 0.42, and 0.40 for daidzein, genistein, and glycitein, respectively, and 0.62, 0.68, and 0.55 for their metabolic products equol, dihydrodaidzein, and O-desmethylangolensin, respectively. These results suggest that the SMHS FFQ can reliably and accurately measure usual intake of isoflavones, and that the levels of isoflavones in urine samples are relatively stable among men in Shanghai.
Sang-Ah Lee; Wanqing Wen; Yong-Bing Xiang; Stephen Barnes; Dake Liu; Qiuyin Cai; Wei Zheng; Xiao Ou Shu
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Validation Studies    
Journal Detail:
Title:  The Journal of nutrition     Volume:  137     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-21     Completed Date:  2007-05-04     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1011-6     Citation Subset:  IM    
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MeSH Terms
Asian Continental Ancestry Group*
Genistein / administration & dosage,  urine
Isoflavones / administration & dosage*,  urine
Middle Aged
Questionnaires / standards*
Reproducibility of Results
Grant Support
P30 CA13148/CA/NCI NIH HHS; R01 CA082729/CA/NCI NIH HHS; R01 CA082729-05/CA/NCI NIH HHS; R01CA82729/CA/NCI NIH HHS; S10 RR 19231/RR/NCRR NIH HHS; U54 CA100949/CA/NCI NIH HHS
Reg. No./Substance:
0/Isoflavones; 0/dihydrodaidzein; 21255-69-6/O-desmethylangolensin; 6287WC5J2L/daidzein; 92M5F28TVF/glycitein; DH2M523P0H/Genistein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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