Document Detail


Assessment of diastolic dysfunction in elderly hypertensive patients using integrated Doppler echocardiography.
MedLine Citation:
PMID:  19484618     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to assess the different stages of diastolic dysfunction (DD) in elderly, asymptomatic, hypertensive patients with preserved systolic function, and to investigate the role of Tissue Doppler imaging (TDI) and Pulmonary venous (PV) flow added to the routine echocardiographic assessment. Patients. 322 patients (age: 70.8+/-9.1 years) were enrolled. METHODS: Mitral inflow pattern, TDI (Ea: early diastolic velocity) and PV flow was assessed to evaluate diastolic function. Deceleration time of mitral E velocity < 150ms, E/Ea> or =7 and/or S/D< 1 of PV flow indicated elevated filling pressure (EFP). Patients were divided into four groups: no DD, mild DD, moderate DD and severe DD. RESULTS: In 63 cases we found no DD, mild DD was present in 150 cases, moderate DD in 86 cases and severe DD in 23 cases. Compared with patients without DD, the Ea was decreased in mild and moderate DD (14.8+/-2.3 vs 12.2+/-2.4 cm/s, p<0.001; vs 13.3+/-2.6 cm/s, p=0.005). Normal mitral inflow pattern was found in 149 patients, 86 of them had EFP (58%). CONCLUSIONS: One third of elderly hypertensive patients with preserved systolic function had moderate-to-severe asymptomatic DD. More than half of the patients had EFP with normal mitral inflow pattern.
Authors:
Mónika Dénes; István Kiss; Mária Lengyel
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Blood pressure     Volume:  18     ISSN:  1651-1999     ISO Abbreviation:  Blood Press.     Publication Date:  2009  
Date Detail:
Created Date:  2010-05-24     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9301454     Medline TA:  Blood Press     Country:  England    
Other Details:
Languages:  eng     Pagination:  135-41     Citation Subset:  IM    
Affiliation:
Gottsegen György Hungarian Institute of Cardiology, Budapest, Budapest, Hungary.
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MeSH Terms
Descriptor/Qualifier:
Aged
Cardiomyopathies / physiopathology,  ultrasonography
Diastole
Echocardiography
Echocardiography, Doppler*
Female
Humans
Hypertension / physiopathology,  ultrasonography
Male
Systole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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