| Assessment of damage to the central nervous system by determination of S-100 protein in the cerebrospinal fluid. | |
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MedLine Citation:
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PMID: 7161607 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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S-100 protein was determined by Particle Counting ImmunoAssay in the CSF of patients with various neurological disorders. With a limit of sensitivity of 2.5 micrograms/l this brain-specific protein was detected only in samples from patients with acute damage of the central nervous system, particularly in compression of the spinal cord by tumour, ischaemic disorders, subarachnoïd bleeding and haematoma, and viral or suspected viral infections. Our results support the assumption that S-100 is a reliable index of central nervous system damage and that changes in its concentration could have a prognostic value. |
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Authors:
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C J Sindic; M P Chalon; C L Cambiaso; E C Laterre; P L Masson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of neurology, neurosurgery, and psychiatry Volume: 45 ISSN: 0022-3050 ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 1982 Dec |
Date Detail:
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Created Date: 1983-04-15 Completed Date: 1983-04-15 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1130-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain Damage, Chronic
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cerebrospinal fluid,
diagnosis* Central Nervous System Diseases / cerebrospinal fluid, diagnosis* Electrophoresis, Polyacrylamide Gel Humans Nerve Tissue Proteins / cerebrospinal fluid* Prognosis S100 Proteins / cerebrospinal fluid* |
| Chemical | |
Reg. No./Substance:
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0/Nerve Tissue Proteins; 0/S100 Proteins |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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