Document Detail

Assessment of cor pulmonale in cystic fibrosis by echocardiography.
MedLine Citation:
PMID:  144404     Owner:  NLM     Status:  MEDLINE    
Thirty-one patients with cystic fibrosis of varying severity were examined by echocardiography. Right ventricular dimension (RVD) was above upper normal limit in 14 patients and right ventricular dimension index (RVD index) was higher than the upper normal limit in 11 patients. Furthermore, there was a significant relationship between increasing RVD index and 1) decreasing forced vital capacity (FVC) both actual test results and average 6 months values; and 2) decreasing peak-expiratory flow rate (PEFR) both actual test results and average 6 months values. This observation suggests a persistent heart involvement. Five patients had either heart failure and/or electrocardiographic evidence of right ventricular abnormality. These patients had increased RVD index and one patient with the highest RVD index died 8 weeks after the examination. The present study has shown the usefulness of echocardiographic measurement of right ventricular dimension and of septal motion in assessing cor pulmonale, before development of electrocardiographic abnormalities and right heart failure.
E Ryssing
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  66     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  753-6     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Cystic Fibrosis / complications*,  diagnosis
Peak Expiratory Flow Rate
Pulmonary Heart Disease / complications,  diagnosis*
Vital Capacity

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