Document Detail

Assessment of cerebral perfusion from bypass arteries using magnetic resonance regional perfusion imaging in patients with moyamoya disease.
MedLine Citation:
PMID:  21191740     Owner:  NLM     Status:  In-Process    
PURPOSE: The purpose of this study was to evaluate whether cerebral perfusion from bypassed arteries can be demonstrated on regional perfusion imaging (RPI) using arterial spin labeling. We then compared cerebral perfusion on RPI and digital subtraction angiography (DSA) in moyamoya patients who underwent extracranial-intracranial bypass surgery.
MATERIALS AND METHODS: We performed RPI using a 3-T magnetic resonance scanner and DSA studies in 11 moyamoya patients treated by bypass surgery. For RPI we placed a selective labeling slab on the bypassed external carotid artery. Two neuroradiologists determined the extent and location of the cerebral perfusion from bypass arteries in the middle cerebral artery territories on RPI and DSA. Kappa analysis was used to assess the interobserver agreement with respect to the extent and location of the cerebral perfusion and to evaluate the intermodality agreement between RPI and DSA.
RESULTS: Interobserver agreement for the extent of cerebral perfusion on RPI was very good (kappa=0.89), with excellent location (kappa=1.00). Intermodality agreement for the extent of perfusion was very good (kappa=0.89), with good location (kappa=0.74).
CONCLUSION: RPI is useful for evaluating cerebral perfusion from bypass arteries in moyamoya patients.
Mika Kitajima; Toshinori Hirai; Yoshinori Shigematsu; Hirofumi Fukuoka; Akira Sasao; Tomoko Okuda; Motohiro Morioka; Yutaka Kai; Yasuyuki Yamashita
Publication Detail:
Type:  Journal Article     Date:  2010-12-30
Journal Detail:
Title:  Japanese journal of radiology     Volume:  28     ISSN:  1867-108X     ISO Abbreviation:  Jpn J Radiol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101490689     Medline TA:  Jpn J Radiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  746-53     Citation Subset:  IM    
Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.
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