Document Detail


Assessment of cardiac reserve in patients with hyperthyroidism.
MedLine Citation:
PMID:  6893178     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Radionuclide multigated cardiac imaging was performed to assess functional cardiac reserve in patients with hyperthyroidism. In 11 normal individuals, submaximl supine exercise increased heart rate (HR) by 60 percent, systolic blood pressure (BP) by 54 percent, and the left ventricular ejection fraction (LVEF) by 13 percent. All of these increments were statistically significant (p < 0.001). Eight patients with hyperthyroidism were studied. Their mean +/- standard error of the mean (SEM) serum thyroxine level was 17.7 +/- 0.5 micrograms percent. There was a negative correlation between serum thyroxine levels and LVEF, both at rest and during exercise, in the patients with hyperthyroidism. Our data suggest that hyperthyroidism is associated with impaired functional cardiac reserve.
Authors:
R B Shafer; J A Bianco
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chest     Volume:  78     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1980 Aug 
Date Detail:
Created Date:  1980-10-27     Completed Date:  1980-10-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  269-73     Citation Subset:  AIM; IM; S    
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Pressure
Cardiac Output
Graves Disease / blood,  physiopathology
Heart / radionuclide imaging
Heart Rate
Hemodynamics*
Humans
Hyperthyroidism / blood,  physiopathology*
Male
Middle Aged
Physical Exertion
Thyroxine / blood
Chemical
Reg. No./Substance:
7488-70-2/Thyroxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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