| Assessment by continuous cardiac monitoring of minimum duration of preoperative propranolol treatment in thyrotoxic patients. | |
| | |
MedLine Citation:
|
PMID: 1269165 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effect of the beta-blocker, propranolol (40 mg 6-hourly orally) has been studied on the tachycardia of six patients with untreated thyrotoxicosis. Heart rate was monitored continuously using a light portable ECG recorder which allowed the patients to undertake normal activities during the recording periods. The most marked reduction in heart rate was evident at 24 h after starting propranolol treatment. In three of the patients there was only a minor further fall in heart rate despite continued propranolol administration, but in the remaining patients the reduction in heart rate with each successive day of treatment was more marked. These results suggest that if propranolol were to be used alone in the preparation of patients before partial thyroidectomy for thyrotoxicosis, a dose of 40 mg 6-hourly for 3-4 days might be sufficient. |
| | |
Authors:
|
A D Toft; W J Irvine; R W Campbell |
Related Documents
:
|
11691525 - An inhibitor of inducible nitric oxide synthase decreases forearm blood flow in patient... 15716285 - Soluble cd40 ligand in acute and chronic heart failure. 16121765 - Concor, an initiative towards a national registry and dna-bank of patients with congeni... 16678485 - Anaemia is an independent predictor of mortality in patients with left ventricular syst... 3707315 - Wound healing in acute spinal cord injury: effect of anticoagulation. 23680435 - Improvements in white matter micro-structural integrity of right uncinate fasciculus an... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical endocrinology Volume: 5 ISSN: 0300-0664 ISO Abbreviation: Clin. Endocrinol. (Oxf) Publication Date: 1976 Mar |
Date Detail:
|
Created Date: 1976-08-02 Completed Date: 1976-08-02 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0346653 Medline TA: Clin Endocrinol (Oxf) Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 195-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Female Heart Rate / drug effects Humans Hyperthyroidism / complications* Male Middle Aged Preoperative Care Propranolol / administration & dosage*, therapeutic use Tachycardia / drug therapy*, etiology Time Factors |
| Chemical | |
Reg. No./Substance:
|
525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Plasma dopamine-beta-hydroxylase activity in phaeochromocytoma.
Next Document: Familial carcinoma of the pancreas.