Document Detail


Assessment by continuous cardiac monitoring of minimum duration of preoperative propranolol treatment in thyrotoxic patients.
MedLine Citation:
PMID:  1269165     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of the beta-blocker, propranolol (40 mg 6-hourly orally) has been studied on the tachycardia of six patients with untreated thyrotoxicosis. Heart rate was monitored continuously using a light portable ECG recorder which allowed the patients to undertake normal activities during the recording periods. The most marked reduction in heart rate was evident at 24 h after starting propranolol treatment. In three of the patients there was only a minor further fall in heart rate despite continued propranolol administration, but in the remaining patients the reduction in heart rate with each successive day of treatment was more marked. These results suggest that if propranolol were to be used alone in the preparation of patients before partial thyroidectomy for thyrotoxicosis, a dose of 40 mg 6-hourly for 3-4 days might be sufficient.
Authors:
A D Toft; W J Irvine; R W Campbell
Related Documents :
11691525 - An inhibitor of inducible nitric oxide synthase decreases forearm blood flow in patient...
15716285 - Soluble cd40 ligand in acute and chronic heart failure.
16121765 - Concor, an initiative towards a national registry and dna-bank of patients with congeni...
16678485 - Anaemia is an independent predictor of mortality in patients with left ventricular syst...
3707315 - Wound healing in acute spinal cord injury: effect of anticoagulation.
23680435 - Improvements in white matter micro-structural integrity of right uncinate fasciculus an...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical endocrinology     Volume:  5     ISSN:  0300-0664     ISO Abbreviation:  Clin. Endocrinol. (Oxf)     Publication Date:  1976 Mar 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0346653     Medline TA:  Clin Endocrinol (Oxf)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  195-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Female
Heart Rate / drug effects
Humans
Hyperthyroidism / complications*
Male
Middle Aged
Preoperative Care
Propranolol / administration & dosage*,  therapeutic use
Tachycardia / drug therapy*,  etiology
Time Factors
Chemical
Reg. No./Substance:
525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Plasma dopamine-beta-hydroxylase activity in phaeochromocytoma.
Next Document:  Familial carcinoma of the pancreas.