Document Detail

Assessment of blocking activity in patients with at least two consecutive spontaneous abortions.
MedLine Citation:
PMID:  1839483     Owner:  NLM     Status:  MEDLINE    
The activity of the blocking factor (BF) was studied in 88 patients affected by recurrent abortion syndrome (RAS) by means of the determination of lymphocyte proliferation rate (LPR) in one-way mixed maternal-paternal lymphocyte cultures (MLC). Forty patients (45.5%) showed inadequate blocking activity (LPR greater than 80%). Pearson's correlation did not reveal any link between patient age and LPR (m2 = 0.031), or between LPR and number of aborted pregnancy (m20.058). Fifteen of the 88 patients had had only two consecutive abortions, but Pearson's correlation did not result in any particular differences in the link between LPR and number of abortions in this group; we therefore felt perfectly justified in extending the study to these subjects.
C Cimino; A Perino; E Cittadini; R Marcenò; A M Cavallaro; G B Granà
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta Europaea fertilitatis     Volume:  22     ISSN:  0587-2421     ISO Abbreviation:  Acta Eur. Fertil.     Publication Date:    1991 May-Jun
Date Detail:
Created Date:  1992-04-28     Completed Date:  1992-04-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1300660     Medline TA:  Acta Eur Fertil     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  177-9     Citation Subset:  IM    
Istituto Materno-Infantile dell'Università di Palermo.
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MeSH Terms
Abortion, Habitual / etiology*
Antigens, Neoplasm / blood*
Gestational Age
Lymphocyte Culture Test, Mixed
Maternal Age
Reg. No./Substance:
0/Antigens, Neoplasm; 0/blocking factor

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