Document Detail


Assessment of biochemical markers of carbofuran toxicity and recovery response in tissues of the freshwater teleost, Clarias batrachus (Linn).
MedLine Citation:
PMID:  18777120     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of a sublethal concentration (7.66 mg/L) of carbofuran, were assessed on Clarias batrachus. The fish were exposed to 7.66 mg of carbofuran/L for 6 days. After 6 days, fish were released into carbofuran-free water in order to study the recovery pattern. Proteins were decreased in gill and kidney and recovery was greater in gill than in kidney. Total amino acids were increased in both tissues. Ammonia level declined in gill and enhanced in kidney throughout the study period. The activities of all enzymes measured were induced in both tissues, except for aspartate aminotransaminase, which was inhibited in gill tissues.
Authors:
Ghousia Begum
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-09-07
Journal Detail:
Title:  Bulletin of environmental contamination and toxicology     Volume:  81     ISSN:  0007-4861     ISO Abbreviation:  Bull Environ Contam Toxicol     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-09-22     Completed Date:  2008-11-17     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0046021     Medline TA:  Bull Environ Contam Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  480-4     Citation Subset:  IM    
Affiliation:
Fisheries Lab, Department of Zoology, College of Science, Osmania University, Hyderabad, 500 007 AP, India. Ghousia786@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Alanine Transaminase / blood
Amino Acids / metabolism
Ammonia / metabolism
Animals
Aspartate Aminotransferases / antagonists & inhibitors,  blood
Biological Markers / analysis*
Carbofuran / toxicity*
Enzyme Induction / drug effects
Fishes / physiology*
Gills / pathology
Glutamate Dehydrogenase / blood
Insecticides / toxicity*
Kidney / pathology
Proteins / metabolism
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Biological Markers; 0/Insecticides; 0/Proteins; 1563-66-2/Carbofuran; 7664-41-7/Ammonia; EC 1.4.1.2/Glutamate Dehydrogenase; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.2/Alanine Transaminase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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