| Assessment of the benzethonium chloride method for routine determination of protein in cerebrospinal fluid and urine. | |
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MedLine Citation:
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PMID: 6821941 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have tested the characteristics of the method of Iwata and Nishikaze (Clin Chem 25: 1317, 1979). The linearity, sensitivity, and precision are satisfactory and the reactivity of benzethonium chloride with various proteins (albumin, immunoglobulins) is the same. The method has been compared with Meulemans's technique (Clin Chim Acta 5: 757, 1960), routinely used in our laboratories, by analysis of 82 samples of cerebrospinal fluid (CSF) and 119 samples of urine. Our results for cerebrospinal fluid agree well with those of Iwata and Nishikaze (r = 0.976; y = 0.992x - 0.013), but we find their method unsuitable for urinary protein determination, probably because of interfering compounds in urine. |
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Authors:
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E Flachaire; O Damour; J Bienvenu; T Aouiti; R Later |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Clinical chemistry Volume: 29 ISSN: 0009-9147 ISO Abbreviation: Clin. Chem. Publication Date: 1983 Feb |
Date Detail:
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Created Date: 1983-03-17 Completed Date: 1983-03-17 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9421549 Medline TA: Clin Chem Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 343-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Albumins
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analysis Benzethonium* Cerebrospinal Fluid Proteins Evaluation Studies as Topic Humans Immunoglobulins / analysis Nephelometry and Turbidimetry Proteins / analysis* Proteinuria Quaternary Ammonium Compounds* Salicylic Acids Spectrophotometry |
| Chemical | |
Reg. No./Substance:
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0/Albumins; 0/Cerebrospinal Fluid Proteins; 0/Immunoglobulins; 0/Proteins; 0/Quaternary Ammonium Compounds; 0/Salicylic Acids; 121-54-0/Benzethonium; 97-05-2/sulfosalicylic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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