Document Detail


Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort.
MedLine Citation:
PMID:  23136642     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Patients with severe or difficult-to-treat asthma account for substantial asthma morbidity, mortality, and healthcare burden despite comprising only a small proportion of the total asthma population. TENOR, a multicenter, observational, prospective cohort study was initiated in 2001. It enrolled 4,756 adults, adolescents and children with severe or difficult-to-treat asthma who were followed semi-annually and annually for three years, enabling insight to be gained into this understudied population. A broad range of demographic, clinical, and patient self-reported assessments were completed during the follow-up period. Here, we present key findings from the TENOR registry in relation to asthma control and exacerbations, including the identification of specific subgroups found to be at particularly high-risk. Identification of the factors and subgroups associated with poor asthma control and increased risk of exacerbations can help physicians design individual asthma management, and improve asthma-related health outcomes for these patients.
Authors:
Bradley E Chipps; Robert S Zeiger; Alejandro Dorenbaum; Larry Borish; Sally E Wenzel; Dave P Miller; Mary Lou Hayden; Eugene R Bleecker; F Estelle R Simons; Stanley J Szefler; Scott T Weiss; Tmirah Haselkorn;
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-20
Journal Detail:
Title:  Current respiratory care reports     Volume:  1     ISSN:  2161-332X     ISO Abbreviation:  Curr Respir Care Rep     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101587973     Medline TA:  Curr Respir Care Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  259-269     Citation Subset:  -    
Affiliation:
Capital Allergy and Respiratory Disease Center, Sacramento, 5609 J Street, Suite C, Sacramento, CA 95819 USA.
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