Document Detail

Assessment of the anemia of chronic disease by digital image processing of erythrocytes.
MedLine Citation:
PMID:  7405894     Owner:  NLM     Status:  MEDLINE    
Eighteen patients with the anemia of chronic disease were studied to determine the usefulness and accuracy of image processing analysis of erythrocytes for diagnosis. Diagnostic tests used for comparison included estimates of serum ferritin, serum iron and iron-binding capacity, stainable marrow iron, and erythrocyte morphology as determined by standard methods. The findings show that the analyses obtained by image processing were diagnostic for 83% of the patients with chronic disease. Serum ferritin levels were supportive of diagnosis for 33% of the patients, and serum iron levels were useful for approximately 25% of the patients. Cell indices and marrow iron were of limited value. The study demonstrates that quantitative information obtained by digital image processing of erythrocytes can be very useful for the diagnosis of the anemia of chronic disease.
M P Westerman; J O'Donnell; J W Bacus
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  74     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1980 Aug 
Date Detail:
Created Date:  1980-10-21     Completed Date:  1980-10-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  163-6     Citation Subset:  AIM; IM    
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MeSH Terms
Anemia / blood*,  diagnosis,  etiology
Chronic Disease
Erythrocyte Indices
Erythrocytes / pathology*
Ferritins / blood
Hemoglobins / analysis
Reg. No./Substance:
0/Hemoglobins; 9007-73-2/Ferritins

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