Document Detail


Assessment of amniotic fluid index in normal pregnancy at a tertiary care hospital setting.
MedLine Citation:
PMID:  20929035     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Ultrasound assessment of amniotic fluid has important implication in obstetrics care and it has become an integral and important component of pregnancy assessment. Changes in amniotic fluid volume are associated with adverse outcome. Excess volume is associated with foetal anomalies and aneuploidy and less volume is associated with Intra Uterine Growth Retardation, renal anomalies in the second trimester. The objective of this study was to establish a normative scale of Amniotic Fluid Index (AFI) throughout gestation in uncomplicated singleton pregnancies, and to identify the lower and upper limits for each gestational week. METHOD: A prospective cross-sectional study conducted in a private tertiary care Hospital from Jan 2004 to April 2005. Amniotic fluid index was calculated in 400 women attending the antenatal clinic. The gestational age of these women range from 20-40 weeks. Women with foetal anomalies, Pregnancy Induced Hypertension, Diabetes Mellitus and other maternal complication were excluded from study. The median, mean, 5th, 50th, and 95th percentile were calculated for each gestation and these values are compared with other studies. RESULTS: The amniotic fluid index observations from regression equation curve were stratified in week-specific normative curves. The mean of preterm was significantly greater than mean of term gestation (p < 0.05). Our median reached peak at 27th week of gestation another peak at 30-31 week. The values then begin a gradual fall to 40 weeks gestation. CONCLUSION: Gestational age specific values of AFI were established, showing significant trends of changes in the amniotic fluid volume with gestation.
Authors:
Habiba Sharaf Ali
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of Ayub Medical College, Abbottabad : JAMC     Volume:  21     ISSN:  1025-9589     ISO Abbreviation:  J Ayub Med Coll Abbottabad     Publication Date:    2009 Jul-Sep
Date Detail:
Created Date:  2010-10-08     Completed Date:  2010-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8910750     Medline TA:  J Ayub Med Coll Abbottabad     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  149-51     Citation Subset:  IM    
Affiliation:
Department of Obstetrics & Gynaecology, Ziauddin University, Karachi, Pakistan. rabel5@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniotic Fluid / ultrasonography*
Cross-Sectional Studies
Female
Gestational Age
Humans
Pregnancy
Prospective Studies
Reference Values
Ultrasonography, Prenatal

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