| Assessment of adenosine-induced coronary steal in the setting of coronary occlusion based on the extent of opacification defects by myocardial contrast echocardiography. | |
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MedLine Citation:
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PMID: 12934764 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors examined the ability of real-time myocardial contrast echocardiography (MCE) to assess adenosine-induced coronary steal in the setting of coronary artery occlusion. The left anterior descending (LAD) coronary artery was occluded in 8 open-chest dogs. Real-time MCE was performed during LAD occlusion, and the extent of opacification defects from MCE was measured without and with adenosine infusion. Microsphere-derived myocardial blood flow (MBF) was measured in the LAD and left circumflex (LCx) coronary artery beds, and the LAD/LCx ratio of MBF was calculated. The LAD/LCx ratio of MBF decreased in response to adenosine administration (without adenosine: 0.66, with adenosine: 0.43, p < 0.01). The extent of opacification defects from MCE increased in response to adenosine administration (without adenosine: 18%, with adenosine: 22%, p < 0.01). Thus, real-time MCE allows for the detection of adenosine-induced coronary steal as changes in the extent of opacification defects in the setting of occlusion of 1 coronary artery accompanying another normally patent coronary artery. |
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Authors:
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Hisashi Masugata; Barry Peters; Stephane Lafitte; G Monet Strachan; Koji Ohmori; Katsufumi Mizushige; Masakazu Kohno |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Angiology Volume: 54 ISSN: 0003-3197 ISO Abbreviation: Angiology Publication Date: 2003 Jul-Aug |
Date Detail:
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Created Date: 2003-08-25 Completed Date: 2003-09-10 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0203706 Medline TA: Angiology Country: United States |
Other Details:
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Languages: eng Pagination: 443-8 Citation Subset: IM |
Affiliation:
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Second Department of Internal Medicine, Kagawa Medical University, 1750-1, Miki, Kita, Kagawa 761-0793, Japan. masugata@kms.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine
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diagnostic use* Animals Arterial Occlusive Diseases / physiopathology, ultrasonography* Collateral Circulation Coronary Circulation* Coronary Disease / physiopathology, ultrasonography* Dogs Echocardiography* |
| Chemical | |
Reg. No./Substance:
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58-61-7/Adenosine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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