Document Detail

Assessment of adenosine-induced coronary steal in the setting of coronary occlusion based on the extent of opacification defects by myocardial contrast echocardiography.
MedLine Citation:
PMID:  12934764     Owner:  NLM     Status:  MEDLINE    
The authors examined the ability of real-time myocardial contrast echocardiography (MCE) to assess adenosine-induced coronary steal in the setting of coronary artery occlusion. The left anterior descending (LAD) coronary artery was occluded in 8 open-chest dogs. Real-time MCE was performed during LAD occlusion, and the extent of opacification defects from MCE was measured without and with adenosine infusion. Microsphere-derived myocardial blood flow (MBF) was measured in the LAD and left circumflex (LCx) coronary artery beds, and the LAD/LCx ratio of MBF was calculated. The LAD/LCx ratio of MBF decreased in response to adenosine administration (without adenosine: 0.66, with adenosine: 0.43, p < 0.01). The extent of opacification defects from MCE increased in response to adenosine administration (without adenosine: 18%, with adenosine: 22%, p < 0.01). Thus, real-time MCE allows for the detection of adenosine-induced coronary steal as changes in the extent of opacification defects in the setting of occlusion of 1 coronary artery accompanying another normally patent coronary artery.
Hisashi Masugata; Barry Peters; Stephane Lafitte; G Monet Strachan; Koji Ohmori; Katsufumi Mizushige; Masakazu Kohno
Related Documents :
2981644 - Two distinct effects of oxygen on vascular tone in isolated porcine coronary arteries.
6795344 - Difference in site and time course of coronary dilating effects of trapidil, nitroglyce...
6130144 - Concentration and time-dependent relationships between isosorbide dinitrate-induced rel...
7586304 - Circadian variation in coronary tone in patients with stable angina. protective role of...
8507974 - Circulatory assist techniques in cardiogenic shock: metabolic aspects.
11524054 - An anti-cd11/cd18 monoclonal antibody in patients with acute myocardial infarction havi...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Angiology     Volume:  54     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:    2003 Jul-Aug
Date Detail:
Created Date:  2003-08-25     Completed Date:  2003-09-10     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  443-8     Citation Subset:  IM    
Second Department of Internal Medicine, Kagawa Medical University, 1750-1, Miki, Kita, Kagawa 761-0793, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenosine / diagnostic use*
Arterial Occlusive Diseases / physiopathology,  ultrasonography*
Collateral Circulation
Coronary Circulation*
Coronary Disease / physiopathology,  ultrasonography*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Relation of thoracic aorta calcification on computed tomography and coronary risk factors to obstruc...
Next Document:  Diabetes mellitus adversely affects the outcomes of thrombolytic therapy in patients with acute myoc...